Obesity Metabolism

Mission

The Obesity and Metabolism Laboratory is focused on understanding the mechanisms that cause obesity and obesity-related complications. By understanding the basis of obesity we are interested in developing strategies to ameliorate obesity and its complications.

Lab Objectives

1. Define the role and mechanisms of adipocyte death in obesity-associated inflammation and metabolic disorders using genetic and nutritional models of adipocyte growth and death.

2. Determine the role of the macrophage in modulating adipocyte death and associated adipose tissue inflammation using genetically altered animal models.

3. Determine the mechanisms by which alterations in Lipid Droplet (LD) proteins modulate lipolysis and risk of developing metabolic disorders.

Staff

Andrew S. Greenberg, M.D.
Director, Obesity and Metabolism Laboratory
Senior Scientist and Associate Professor, Endocrinology, Metabolism, and Molecular Medicine, Nutrition
Research focus: Etiology of obesity and its complications; the role of inflammation in metabolic disorders and the regulation of adipocyte metabolism, inulin resistance, and diabetes

Martin Obin, Ph.D.
Scientist I and Associate Professor, Nutrition
Research focus: nutrient effects on obesity-associated complications and aging

Katherine Strissel, Ph.D.
Scientist III
Research focus: potential role(s) of macrophage infiltration of obese adipose tissue in progression towards type II diabetes

Qing-Wu Yan, Ph.D.
Scientist III
Research focus: Excess calorie-related metabolic complications - obesity, insulin resistance, type 2 diabetes

Yunkyoung Lee, Ph.D. Postdoctoral Associate
Research focus: the role of obesity-associated inflammation in metabolic disorders

Eugene Chang, Ph.D. Postdoctoral Associate

Brooke Hasson, Ph.D. Postdoctoral Associate

Victoria Vieira, Ph.D. Postdoctoral Associate

Sajid Hussain, MD Postdoctoral Associate

You-Ree Cho, Ph.D. Research Associate

Chen Xie, B.A. Research Technician

Jason DeFuria Graduate Student

Grace Bennett, M.S. Graduate Student

Vladimir Kustanovich, B.S. Graduate Student

Mary Beth Keith, Budget and Administrative Assistant

For contact information, please click on the scientist's webpage or visit the Tufts University online directory at http://whitepages.tufts.edu/.

Obesity Metabolism

Learn More