Human Nutrition Research Center on Aging - Tufts University

Current Projects

  • Determine effects of dietary fat on the bioavailability of provitamin A carotenoids in biofortified rice.
  • Determine the vitamin A equivalence of plant carotenoids in children, using deuterium-labeled spinach, Golden Rice, and pure beta-carotene in Chinese children.
  • Determine the vitamin A equivalence of spirulina in adults with and without vitamin A
  • Determine the vitamin A equivalence of yellow
  • Determine the bioavailability of lutein and zeaxanthin/capsanthin from peppers in humans.
  • Evaluate the effect of nutritional supplements on the progression of retinal disease.
  • Examine the relationship between serum levels of antioxidants and the presence of age-related maculopathy.
  • Determine the changes in macular pigment density of the eye and changes in antioxidant capacity in the circulation when consuming lutein
  • Determine the major factors affecting antioxidant capacity in humans and to modify antioxidant capacity by supplementing with antioxidant nutrients.
  • Elucidate effects of bioactive plant-based foods on biological functions and genomic stability in humans.
  • Examine the functions of dipeptides as a quencher of cytotoxic carbonic compounds.
  • Evaluate the role of lipoprotein subpopulations in macular pigmentation.
  • Develop a database of individual levels of lutein and zeaxanthin in their major food sources in the U.S. diet.
  • Apply the lutein and zeaxanthin food database to determine their individual intakes in populations.
  • Determine the role of xanthophylls in cognitive function

 

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