Vitamins and Carcinogenesis Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3117
Fax: (617) 556-3309
Ph.D Nutrition, Auburn University, Alabama
Epigenetic/genetic mechanisms underlying the mediation of tumorigenic pathways by one-carbon metabolism and related gene variances. Nutrition and biomarkers that may be in relation to the prevention of cancer and other diseases.
|Selected Professional Affiliations||American Association of Cancer Research|
Selected Research Publications
Liu, Z. S. Choi, J. W. Crott, J. B. Mason. Inadequate intake of multiple B-vitamins amplifies alterations in p53 expression and function induced by isolated folate depletion. International Journal of Cancer. 2008; 123: 519-525.
Crott, J. W., Z. Liu, M. K. Keyes, S. Choi, H. Jang, M. P. Moyer, J. B. Mason. Moderate folate depletion modulates the expression of selected genes involved in cell cycle, intracellular signaling, and folate uptake in human colonic epithelial cell lines. Journal of Nutritional Biochemistry. 2008; 19: 328-335.
Liu, Z., S. Choi, J. W. Crott, M. K. Keyes, H. Jang, D. E. Smith, M. Kim, P. W. Laird, R. Bronson, J. B. Mason. Mild depletion of dietary folate combined with other B-vitamins alters multiple components of the Wnt pathway in the mouse colon. Journal of Nutrition. 2007; 137: 2701-2708.
Keys, M. K, H. Jang, J. B. Mason, Z. Liu, J. W. Crott, D. E. Smith, S. Friso, S. Choi. Elder age and dietary folate are interactive determinants of genomic and p16-specific DNA methylation in the mouse colon. Journal of Nutrition. 2007; 137:1713-1717.
Crott, J. W., Z. Liu, S. Choi, J. B. Mason. Folate depletion in human lymphocytes up-regulates p53 expression despite marked induction of strand breaks in exons 5–8 of the gene. Mutation Research. 2007; 626:171-179.
To see more of Dr. Zhenhua Liu's publications, please visit PubMed and search for "Liu Z."