Dayong Wu, M.D., Ph.D.
Nutritional Immunology Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3368
Fax: (617) 556-3224
M.D., Norman Bethune University of Medical Sciences, China
Ph.D., Immunology, Jilin University, Bethune School of Medicine
||Effects of dietary lipids and antioxidant nutrients on immune and inflammatory responses; eicosanoid metabolism and immune function; molecular mechanisms of age-related changes in immune cells
||Assistant Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University
|Selected Professional Affiliations
||Member, American Society for Nutritional Sciences
Member, American Aging Association
Featured HNRCA Research Publications
Ren Z, Guo Z, Meydani SN, Wu D. White button mushroom enhances maturation of bone marrow derived dendritic cells and their antigen presenting function in mice. J. Nutr. 138:544-550. 2008.
Wu, D., Ren, Z., Pae, P., Guo, W., Cui, X.,Merrill, A.H., Meydani, S.N.. Aging up-regulates expression of inflammatory mediators in mouse adipose tissue. J. Immunol. 179:4829-4839. 2007.
Wu, D., Han, S.N., Meydani, M Meydani. Effect of concomitant consumption of fish oil and vitamin E on T cell mediated function in the elderly: a randomized double-blind trial. J Am Coll Nutr. 25: 300-306. 2006.
Wu, D., Liu, L., Meydani, M., Meydani, S.N. Vitamin E increases production of vasodilator prostanoids in human aortic endothelial cells through opposing effects on cyclooxygenase-2 and phospholipase A2. J. Nutr. 135:1847-1853. 2005.
Wu, D., Marko, M., Claycombe, K.J., Paulson, K.E., Meydani, S.N. Ceramide-induced and age-associated increase in macrophage COX-2 expression is mediated through upregulation of NF-?B activity. JBC. 278: 10983-10992. 2003.
Other Recent Publications
Wu, D., Pae, M., Ren, Z., Guo, Z., Donald Smith, Meydani, S.N. Dietary Supplementation with White Button Mushroom Enhances Natural Killer Cell Activity in C57BL/6 Mice. J. Nutr. 137: 1472-1477. 2007.
Chang J, Sukhova G, Libby P, Schvartz E, Lichtenstein A H, Field S, Kennedy C, Madhavarapu S, Luo J, Wu D, Cantley L. Deletion of the phosphoinositide 3-Kinase p110(gamma) gene attenuates murine atherosclerosis. Proc Nat Acad Sci 2007;104:19.
Meydani SN, Han SN, Wu D. Vitamin E and immune response in the aged: molecular mechanisms and clinical implications. Immunol Rev 2005;205:269-284.
Wu D, Liu L, Meydani M, Meydani SN. Effect of vitamin E on prostacyclin (PGI2) and prostaglandin (PG) E2 production by human aorta endothelial cells: mechanism of action. Ann N Y Acad Sci 2004;1031:425-427.
Wu D, Han SN, Meydani M, Meydani SN. Effect of concomitant consumption of fish oil and vitamin E on production of inflammatory cytokines in healthy elderly humans. Ann N Y Acad Sci 2004;1031:422-424.
Ahmed T, Marko M, Wu D, Chung HY, Huber B, Meydani SN.
Vitamin E supplementation reverses the age-associated decrease in effective immune synapse formation in CD4+ T cells. Ann N Y Acad Sci 2004;1031:412-414.
Wu D, Meydani SN. Mechanism of age-associated up-regulation in macrophage PGE2 synthesis. Brain Behav Immun 2004;18 (6):487-494.
Wu D, Han SN, Meydani M, Meydani SN. Concurrent consumption of fish oil does not substantially interfere with the immuno-enhancing effect of vitamin E in the healthy elderly humans. New York Academy of Sciences 2004;6.
Wu D, Liu L, Meydani M, Meydani SN. Effect of vitamin E (E) on prostacyclin (PGI2) and prostaglandin (PG) E2 production by human aorta endothelial cell (HAEC) and its mechanism. New York Academy of Sciences 2004;12.
Wu D. Modulation of immune and inflammatory responses by dietary lipids. Curr Opin Lipidol 2004;15(1):43-47.
To see more of Dr. Dayong Wu's publications, please visit PubMed and search for "Wu D."