Laboratory for Nutrition and Vision Research
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3094
Fax: (617) 556-3132
|Education||Ph.D., Molecular Biology
Illinois Institute of Technology
|Research Focus||Effects of nutrition, oxidation, and protein degradation on etiology of age-related eye disorders; identification of lens or retinal substrates for the ubiquitin dependent pathway and of specific enzymes involved in the recognition of damaged proteins|
Featured HNRCA Research Publications
Zhang X, Dudek EJ, Liu B, Ding L, Fernandes AF, Liang JJ, Horwitz J, Taylor A, Shang F. Degradation of c-terminal truncated alpha A-crystallins by the ubiquitin-proteasome pathway. IOVS. 2007;48:4200-8.
Shang F, Dudek E, Liu Q, Boulton ME, Taylor A. Protein quality control by the ubiquitin proteolytic pathway: roles in resistance to oxidative stress and disease. Israel J Chem. 2006;46:145-158.
Dudek EJ, Shang F, Liu C, Valverde P, Hobbs ML, Taylor A. Selectivity of the ubiquitin pathway for oxidatively modified proteins: relevance to protein precipitation diseases. FASEB J. 2005;19(12):1707-9.
Shang F, Lu M, Dudek EJ, Reddan JR, Taylor A. Vitamin C and vitamin E restore the resistance of GSH-depleted lens cells to H2O2. Free Radic Biol Med. 2003;34(5):521-530.
Dudek EJ, Shang F, Taylor A. H2O2-mediated oxidative stress activates NF-kappa B in lens epithelial cells. Free Radic Biol Med. 2001;31:651-8.
To see more of Dr. Edward Dudek's publications, please visit PubMed and search for "Dudek E."