2480: Gene/Diet Effects on Plasma Lipoprotein Levels
Caribbean Hispanic men and women, aged 18 years and older
To determine the effect of a Hispanic Diet (low fat) and an American Diet (high fat) on levels of cholesterol and other blood markers that may increase risk of developing heart disease.
- Diabetes mellitus (fasting blood sugar >140 mg/dl)
- Uncontrolled hypertension (blood pressure > 180/100 mmHg
- Liver disease, severe kidney dysfunction, angina pectoris, or significant endocrine disease
- Preexisting cardiovascular disease or gallbladder disease, or pancreatitis within last 12 months
- Lipid lowering medications
- Body mass index > 34 kg/m2
- Excessive alcohol consumption (> 2 drinks/day)
- Smoking within the past 6 months, or drug abuse
- Pregnancy or breastfeeding
- Weight gain or loss of more than 20 lbs within the past 6 months
- Strict vegetarians
- Egg, wheat, milk, fish or nut allergies
- Travel plans that preclude availability for the two 4-week study phases
|Length of Study
Two phases of 4 weeks each, with a break of 2-8 weeks in between phases
|# of Visits
1 screening visit and 12 visits per study phase (3 times per week, most likely Monday, Wednesday, and Friday mornings
1-3 hrs per visit and one visit of 9 hrs per study phase, no overnight stays
Two diets, a low-fat Hispanic diet and a high-fat American diet. All food and beverages are provided during the two 4-week phases. We ask that you eat 3 meals per week (breakfast) at the Center.
$15 for screening visit, and $1000 for qualifying and completing both study phases
|Can I work?
Yes, around study visits
Questionnaires, body composition and blood pressure measurements, blood and urine samples, heparin test, oral glucose tolerance test (OGTT), and oral fat load test.
- Length of study
Total length of the study including resident stays and nonresident visits.
This does not mean you will be testing the entire time.
The length of time volunteers are required to stay overnight at the HNRCA. Residents have their own private room, bathroom, television, VCR, and phone during their stay.
The amount of reimbursement for travel and inconvenience.
- Number of visits
Total number of nonresident visits.
- Study diet
Indicates meals which will be provided by the HNRCA
- Can I work?
Indicates if you will be able to work and if so, when.
For more information on this study, please call (617) 556-3286 or e-mail Study2480
We appreciate your interest in our program and we hope to work with you in the future.
The Recruitment Office
Jean Mayer USDA Human Nutrition Research Center on Aging at Tufts University