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Scientist I Vitamins and Carcinogenesis Laboratory Jean Mayer USDA HNRCA at Tufts University 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3007 Fax: (617) 556-3234 E-mail: sang.choi@tufts.edu |
| Education | M.D., Seoul National University Ph.D., Medical Science, Seoul National University |
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| Research Focus | Mechanisms underlying the modulation of carcinogenesis by one-carbon metabolism, aging, and epigenetics |
| Selected Professional Affiliations | Associate Professor at the Friedman School of Nutrition Science and Policy at Tufts University |
| Board Certification | Korean Board of Gastroenterology Korean Board of Internal Medicine |
Recent Publications |
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| Friso S, Lotto V, Choi SW, Girelli D, Pinotti M, Guarini P, Udali S, Pattini P, Pizzolo F, Martinelli N, Corrocher R, Bernardi F, Olivieri O. Promoter methylation in coagulation F7 gene influences plasma FVII concentrations and relates to coronary artery disease. J Med Genet. 2012 Feb 7.
Park LK, Friso S, Choi SW. Nutritional influences on epigenetics and age-related disease. Proc Nutr Soc. 2012 Feb;71(1):75-83. Friso S, Lotto V, Corrocher R, Choi SW. Vitamin b6 and cardiovascular disease. Subcell Biochem. 2012;56:265-90. Choi SW, Friso S. Vitamins b6 and cancer. Subcell Biochem. 2012;56:247-64. Sie KK, Medline A, van Weel J, Sohn KJ, Choi SW, Croxford R, Kim YI. Effect of maternal and postweaning folic acid supplementation on colorectal cancer risk in the offspring. Gut. 2011 Dec;60(12):1687-94. Liu Z, Ciappio ED, Crott JW, Brooks RS, Nesvet J, Smith DE, Choi SW, Mason JB.C ombined inadequacies of multiple B vitamins amplify colonic Wnt signaling and promote intestinal tumorigenesis in BAT-LacZxApc1638N mice. FASEB J. 2011 Sep;25(9):3136-45. Dawlaty MM, Ganz K, Powell BE, Hu YC, Markoulaki S, Cheng AW, Gao Q, Kim J, Choi SW, Page DC, Jaenisch R. Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development. Cell Stem Cell. 2011 Aug 5;9(2):166-75. Lotto V, Choi SW, Friso S.Vitamin B6: a challenging link between nutrition and inflammation in CVD. Br J Nutr. 2011 Apr 13:1-13. Kim KC, Jang H, Sauer J, Zimmerly EM, Liu Z, Chanson A, Smith DE, Friso S, Choi SW. Folate supplementation differently affects uracil content in DNA in the mouse colon and liver. Br J Nutr. 2011 Mar;105(5):688-93. Tong SY, Kim MK, Lee JK, Lee JM, Choi SW, Friso S, Song ES, Lee KB, Lee JP. Common polymorphisms in methylenetetrahydrofolate reductase gene are associated with risks of cervical intraepithelial neoplasia and cervical cancer in women with low serum folate and vitamin B12. Cancer Causes Control. 2011 Jan;22(1):63-72. Choi SW, Friso S. Epigenetics: A New Bridge between Nutrition and Health. Adv Nutr. 2010 Nov;1(1):8-16. Al Rajabi A, Peterson J, Choi SW, Suttie J, Barakat S, Booth SL. Measurement of menadione in urine by HPLC. J Chromatogr B Analyt Technol Biomed Life Sci. 2010 Sep 15;878(26):2457-60. Sauer J, Jang H, Zimmerly EM, Kim KC, Liu Z, Chanson A, Smith DE, Mason JB, Friso S, Choi SW. Ageing, chronic alcohol consumption and folate are determinants of genomic DNA methylation, p16 promoter methylation and the expression of p16 in the mouse colon. Br J Nutr. 2010 Jul;104(1):24-30. Kim KC, Friso S, Choi SW. DNA methylation, an epigenetic mechanism connecting folate to healthy embryonic development and aging. J Nutr Biochem. 2009 Dec;20(12):917-26. Sohn KJ, Jang H, Campan M, Weisenberger DJ, Dickhout J, Wang YC, Cho RC, Yates Z, Lucock M, Chiang EP, Austin RC, Choi SW, Laird PW, Kim YI. The methylenetetrahydrofolate reductase C677T mutation induces cell-specific changes in genomic DNA methylation and uracil misincorporation: a possible molecular basis for the site-specific cancer risk modification. Int J Cancer. 2009 May 1;124(9):1999-2005. |
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