|Scientist I and Director
Vitamins and Carcinogenesis Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3194
Fax: (617) 556-3234
|Education||M.D., University of Chicago
Pritzker School of Medicine
|Research Focus||Folate and carcinogenesis, intestinal metabolism of folate|
|Academic Appointments||Associate Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University
Associate Professor, Tufts University School of Medicine
|Selected Professional Affiliations||Member, Professional Education Committee, American Society for Nutritional Sciences
Editorial Board, JPEN - Journal of Parenteral and Enteral Nutrition
|Board Certification||Internal Medicine
Liu Z, Brooks RS, Ciappio ED, Kim SJ, Crott JW, Bennett G, Greenberg AS, Mason JB. Diet-induced obesity elevates colonic TNF-alpha in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer. J Nutr Biochem. 2011 Dec 29. [Epub ahead of print]
Ciappio ED, Liu Z, Brooks RS, Mason JB, Bronson RT, Crott JW. Maternal B vitamin supplementation from preconception through weaning suppresses intestinal tumorigenesis in Apc1638N mouse offspring. Gut. 2011 Dec;60(12):1695-702.
Mason JB. Folate consumption and cancer risk: a confirmation and some reassurance, but we're not out of the woods quite yet. Am J Clin Nutr. 2011 Oct;94(4):965-6.
Tao MH, Mason JB, Marian C, McCann SE, Platek ME, Millen A, Ambrosone C, Edge SB, Krishnan SS, Trevisan M, Shields PG, Freudenheim JL.Promoter methylation of E-cadherin, p16, and RAR-beta(2) genes in breast tumors and dietary intake of nutrients important in one-carbon metabolism. Nutr Cancer. 2011 Oct;63(7):1143-50.
Ciappio ED, Mason JB, Crott JW. Maternal one-carbon nutrient intake and cancer risk in offspring. Nutr Rev. 2011 Oct;69(10):561-71.
Liu Z, Ciappio ED, Crott JW, Brooks RS, Nesvet J, Smith DE, Choi SW, Mason JB. Combined inadequacies of multiple B vitamins amplify colonic Wnt signaling and promote intestinal tumorigenesis in BAT-LacZxApc1638N mice. FASEB J. 2011 Sep;25(9):3136-45.
Tomaszewski JJ, Cummings JL, Parwani AV, Dhir R, Mason JB, Nelson JB, Bacich DJ, O'Keefe DS. Increased cancer cell proliferation in prostate cancer patients with high levels of serum folate. Prostate. 2011 Sep;71(12):1287-93. d
Mason JB.Unraveling the complex relationship between folate and cancer risk. Biofactors. 2011 Jul;37(4):253-60.
Protiva P, Mason JB, Liu Z, Hopkins ME, Nelson C, Marshall JR, Lambrecht RW, Pendyala S, Kopelovich L, Kim M, Kleinstein SH, Laird PW, Lipkin M, Holt PR. Altered folate availability modifies the molecular environment of the human colorectum: implications for colorectal carcinogenesis. Cancer Prev Res (Phila). 2011 Apr;4(4):530-43.
Flood A, Mason JB, Liu Z, Cash BD, Schatzkin A, Schoenfeld PS, Cross AJ.Concentration of folate in colorectal tissue biopsies predicts prevalence of adenomatous polyps. Gut. 2011 Jan;60(1):66-72.
Mason JB, Baron JA. Effects of folic acid plus vitamin B12 vs placebo in myocardial infarction survivors. JAMA. 2010 Oct 27;304(16):1783; author reply 1783-4.
Mason JB, Kim SJ. Revisiting the goldilocks phenomenon: folate and colorectal cancer risk. Am J Gastroenterol. 2010 Sep;105(9):1914-6.
Sauer J, Jang H, Zimmerly EM, Kim KC, Liu Z, Chanson A, Smith DE, Mason JB, Friso S, Choi SW. Ageing, chronic alcohol consumption and folate are determinants of genomic DNA methylation, p16 promoter methylation and the expression of p16 in the mouse colon. Br J Nutr. 2010 Jul;104(1):24-30.
Chanson A, Parnell LD, Ciappio ED, Liu Z, Crott JW, Tucker KL, Mason JB. Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population. Am J Clin Nutr. 2009 Jun;89(6):1927-36.
Sauer J, Mason JB, Choi SW. Too much folate: a risk factor for cancer and cardiovascular disease? Curr Opin Clin Nutr Metab Care. 2009 Jan;12(1):30-6.