Nutrition and Cancer Biology Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3106
Fax: (617) 556-3344
|Education||Ph.D., Nutrition, Tufts University
M.S., Biochemistry, Shanghai Medical University, China
M.D., Shanghai Medical Univeristy, China
|Research Focus||Carotenoids, retinoids, and carcinogenesis|
|Selected Professional Affiliations||International Carotenoid Society
Selected Research Publications
Lian, F., Wang, X. Enzymatic metabolites of lycopene induce Nrf2-mediated expression of phase II detoxifying/antioxidant enzymes in human bronchial epithelial cells. International Journal of Cancer. 2008;123:1262-1268.
Lian, F., Smith, D., Ernst, H., Russell, R., Wang, X. Apo-10'-lycopenoic acid suppresses lung cancer cell growth by activating retinoic acid receptor Beta in vitro, and inhibits lung tumorigenesis in vivo in the A/J mouse model. Carcinogenesis. 2007;28:1567-1574.
Lian, F., Hu, K., Russell, R., Wang, X. Beta-Cryptoxanthin Suppresses the Growth of Immortalized Human Bronchial Epithelial Cells. International Journal of Cancer. 2006;119:2084-2089.
Lian, F., Chung, J., Russell, R.M., Wang, X. Alcohol-reduced plasma IGF-1 levels and hepatic IGF-1 expression can be partially restored by retinoic acid supplementation in rats. Journal of Nutrition. 2004;134:2953-2956.
Liu, C., Lian, F., Smith, D.E., Russell, R.M., Wang, X. Lycopene supplementation inhibits lung squamous metaplasia and induces apoptosis via up-regulating insulin-like growth factor-binding protein 3 in cigarette smoke-exposed ferrets. Cancer Research. 2003;63:3138-3144.
To see more of Dr. Fuzhi Lian's publications, please visit PubMed and search for "Lian F."