Zhenhua Liu, Ph.D.

Recent Publications
	Scientist III Vitamins and Carcinogenesis Laboratory Jean Mayer USDA HNRCA at Tufts University 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3117 Fax: (617) 556-3309 E-mail: zhenhua.liu@tufts.edu
Education	Ph.D Nutrition, Auburn University, Alabama M.S. Statistics, Auburn Unveristy, Alabama M.S. Animal Sciences, China Agricultural University, Beijing, China B.S. Animal Sciences, Hunan Agricultural University, Hunan, China
Research Focus	Epigenetic/genetic mechanisms underlying the mediation of tumorigenic pathways by one-carbon metabolism and related gene variances. Nutrition and biomarkers that may be in relation to the prevention of cancer and other diseases.
Selected Professional Affiliations	American Association of Cancer Research
Liu Z, Brooks RS, Ciappio ED, Kim SJ, Crott JW, Bennett G, Greenberg AS, Mason JB. Diet-induced obesity elevates colonic TNF-alpha in mice and is accompanied by an activation of Wnt signaling: a mechanism for obesity-associated colorectal cancer. J Nutr Biochem. 2011 Dec 29. [Epub ahead of print] Ciappio ED, Liu Z, Brooks RS, Mason JB, Bronson RT, Crott JW. Maternal B vitamin supplementation from preconception through weaning suppresses intestinal tumorigenesis in Apc1638N mouse offspring. Gut. 2011 Dec;60(12):1695-702. Liu Z, Ciappio ED, Crott JW, Brooks RS, Nesvet J, Smith DE, Choi SW, Mason JB. Combined inadequacies of multiple B vitamins amplify colonic Wnt signaling and promote intestinal tumorigenesis in BAT-LacZxApc1638N mice. FASEB J. 2011 Sep;25(9):3136-45. Chen CY, Crott J, Liu Z, Smith DE. Fructose and saturated fats predispose hyperinsulinemia in lean male rat offspring. Eur J Nutr. 2010 Sep;49(6):337-43. Sauer J, Jang H, Zimmerly EM, Kim KC, Liu Z, Chanson A, Smith DE, Mason JB, Friso S, Choi SW. Ageing, chronic alcohol consumption and folate are determinants of genomic DNA methylation, p16 promoter methylation and the expression of p16 in the mouse colon. Br J Nutr. 2010 Jul;104(1):24-30. Chanson A, Parnell LD, Ciappio ED, Liu Z, Crott JW, Tucker KL, Mason JB. Polymorphisms in uracil-processing genes, but not one-carbon nutrients, are associated with altered DNA uracil concentrations in an urban Puerto Rican population. Am J Clin Nutr. 2009 Jun;89(6):1927-36.