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Senior Scientist and Director Nutrition and Cancer Biology Laboratory Jean Mayer USDA HNRCA at Tufts University 711 Washington Street Boston, MA 02111-1524 Phone: (617) 556-3130 Fax: (617) 556-3344 E-mail: xiang-dong.wang@tufts.edu |
| Education | M.D., Peking Medical University Ph.D., Nutrition, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University |
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| Research Focus | Carotenoids; retinoids; carcinogenesis |
| Academic Appointments | Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University Associate Professor, Tufts University School of Medicine Co-Leader, Nutrition and Cancer Prevention Program, Cancer Center, Tufts Medical Center |
| Selected Professional Affiliations | American Society of Nutrition American Society of Cancer Research |
| Board Certification | Medicine (China) |
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| Recent Publications | |
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Liu C, Bronson RT, Russell RM, Wang X-D. Chemopreventive effect of b-cryptoxanthin on smoke-induced lung inflammation and neoplasia in ferrets. Cancer Prev Res 2011; In press: Epub ahead of print. Mein J, Dolinkowski G, Russell RM, Wang X-D. Enzymatic formation of apo-carotenoids from the xanthophyll carotenoids lutein, zeaxanthin and beta-cryptoxanthin by ferret Carotene-9?, 10?-Monooxygenase. Arch Biochem Biophys 2011; 506: 109-121. Chavez PRG, Lian F, Chung J, Liu C, Paiva SAR, Seitz HK, Wang X-D. Long-term ethanol consumption promotes hepatic tumorigenesis but impairs normal hepatocyte proliferation in rats. J Nutr 2011; 141: 1049-55. Tang FY, Pai MH, Wang X-D. Consumption of lycopene inhibits the growth and progression of colon cancer in a mouse xenograft model. J. Agric. Food Chem. 2011; In press: Epub ahead of print. Kim Y, Chongyviriyaphan N, Liu C, Russell RM, Wang X-D. Combined a-tocopherol and ascorbic acid protects against smoke-induced lung squamous metaplasia in ferrets. Lung Cancer 2011; 73: 283-288. Nascimento AF, Luvizotto RAM., Leopoldo AS, Seiva FR, Justulin LA, Silva MDP, Okoshi K, Wang X-D, Cicohna AC. Long-term high fat diet induced obesity decreases the cardiac leptin receptor without apparent lipotoxicity. Life Science 2011; 88: 1031-1038. Wang Y, Ausman LM, Greenberg AS, Russell RM, Wang X-D. Dietary lycopene and tomato extract supplementations inhibit nonalcoholic steatohepatitis-promoted hepatocarcinogenesis in rats. Int J Cancer 2010; 126: 1788-1796. Luvizotto RAM., Nascimento AF, Veeramachaneni S, Liu C, Wang X-D. Chronic Alcohol Intake Up-regulates Hepatic Expressions of Carotenoid Cleavage Enzymes and Peroxisomal Proliferator-Activated Receptors in Rats. J Nutr 2010; 140: 1808-1814. Wang Y, Seitz HK, Wang X-D. Moderate alcohol consumption aggravates high-fat diet induced steatohepatitis in rats. Alcoholism Clinical Exp. Research 2010; 34: 567-73. Zhang Y, Lian F, Zhu Y, Xia M, Wang Q, Ling W, Wang X-D. Cyanidin-3-O-b-glucoside inhibits LPS-induced expression of inflammatory mediators through decreasing I?B? phosphorylation in THP-1 Cells. Inflammation Research 2010; 59: 723-730. Wang X-D. Biological activities of carotenoid metabolites. In: ?Carotenoids? eds, Britton, Jensen, and Pfander Birkhauser Verlag Press, pp. 383-408, 2010. Mernitz H, Lian F, Smith D, Meydani SN, Wang X-D. Fish oil supplementation inhibits NNK-induced lung carcinogenesis in the A/J mouse. Nutr and Cancer 2009; 61: 663-669. Wang Y, Ausman LM, Greenberg AS, Russell RM, Wang X-D. Nonalcoholic steatohepatitis induced by a high-fat diet promotes diethylnitrosamine initiated early hepatocarcinogenesis in rats. Int J Cancer 2009; 124: 540-546. Liu C, Wang X-D, Mucci L, Gaziano JM, Zhang SM. Modulation of lung molecular biomarkers by beta-carotene in the Physicians? Health Study. Cancer 2009; 115: 1049-58. Chung J, Veeramachaneni S, Liu C, Mernitz H, Russell RM, Wang X-D. Vitamin E supplementation does not prevent ethanol-reduced hepatic retinoic acid levels in rats. Nutrition Research 2009; 29: 664-670. |
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