Nutritional Immunology Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3368
Fax: (617) 556-3224
M.D., Norman Bethune University of Medical Sciences, China
|Research Focus||Effects of dietary lipids and antioxidant nutrients on immune and inflammatory responses; eicosanoid metabolism and immune function; molecular mechanisms of age-related changes in immune cells|
|Academic Appointments||Assistant Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University|
|Selected Professional Affiliations||Member, American Society for Nutritional Sciences
Member, American Aging Association
Wang J, Pae M, Meydani SN, Wu D. Epigallocatechin-3-Gallate Inhibits Expression of Receptors for T Cell Regulatory Cytokines and Their Downstream Signaling in Mouse CD4+ T Cells. J Nutr. 2012 Mar;142(3):566-71.
Zhao JC, Yu J, Runkle C, Wu L, Hu M, Wu D, Liu JS, Wang Q, Qin ZS, Yu J. Cooperation between Polycomb and androgen receptor during oncogenic transformation. Genome Res. 2012 Feb;22(2):322-31.
Wu D, Wang J, Pae M, Meydani SN. Green tea EGCG, T cells, and T cell-mediated autoimmune diseases. Mol Aspects Med. 2012 Feb;33(1):107-18.
Bian Q, Qin T, Ren Z, Wu D, Shang F. Lutein or zeaxanthin supplementation suppresses inflammatory responses in retinal pigment epithelial cells and macrophages. Adv Exp Med Biol. 2012;723:43-50.
Wang J, Ren Z, Xu Y, Xiao S, Meydani SN, Wu D. Epigallocatechin-3-gallate ameliorates experimental autoimmune encephalomyelitis by altering balance among CD4+ T-cell subsets. Am J Pathol. 2012 Jan;180(1):221-34.
Wu D, Zhang C, Shen Y, Nephew KP, Wang Q. Androgen receptor-driven chromatin looping in prostate cancer. Trends Endocrinol Metab. 2011 Dec;22(12):474-80.
Zhang C, Wang L, Wu D, Chen H, Chen Z, Thomas-Ahner JM, Zynger DL, Eeckhoute J, Yu J, Luo J, Brown M, Clinton SK, Nephew KP, Huang TH, Li W, Wang Q. Definition of a FoxA1 Cistrome that is crucial for G1 to S-phase cell-cycle transit in castration-resistant prostate cancer. Cancer Res. 2011 Nov 1;71(21):6738-48. Epub 2011 Sep 7. Erratum in: Cancer Res. 2011 Dec 15;71(24):7718.
Wu D, Wang J. The ability of green tea to alleviate autoimmune diseases: fact or fiction? Expert Rev Clin Immunol. 2011 Nov;7(6):711-3.
Wang H, Wu D, Li D, Niu Z, Chen Y, Tang D, Wu M, Cao J, Huang Y. Fabrication of continuous highly ordered mesoporous silica nanofibre with core/sheath structure and its application as catalyst carrier. Nanoscale. 2011 Sep 1;3(9):3601-4.
Wang H, Zhang C, Rorick A, Wu D, Chiu M, Thomas-Ahner J, Chen Z, Chen H, Clinton SK, Chan KK, Wang Q. CCI-779 inhibits cell-cycle G2-M progression and invasion of castration-resistant prostate cancer via attenuation of UBE2C transcription and mRNA stability. Cancer Res. 2011 Jul 15;71(14):4866-76.
Pae M, Ren Z, Meydani M, Shang F, Smith D, Meydani SN, Wu D. Dietary supplementation with high dose of epigallocatechin-3-gallate promotes inflammatory response in mice. J Nutr Biochem. 2011 Jun 16.
Chen Z, Zhang C, Wu D, Chen H, Rorick A, Zhang X, Wang Q. Phospho-MED1-enhanced UBE2C locus looping drives castration-resistant prostate cancer growth. EMBO J. 2011 May 10;30(12):2405-19.
Pei S, Ma H, Shi B, Wu D, Zhou W. A new species of Lithobius (Monotarsobius) Verhoeff, 1905 (Lithobiomorpha, Lithobiidae) from China. Zookeys. 2011 Feb 23;(82):59-66.
Luo Q, Wu D, Liu S, Tang D, Huang Y, Liu X, Wang F, Wang R, Wu G. The formation of thymidine-based T-tetramers with remarkable structural and metal ion size effects. Org Biomol Chem. 2011 Feb 21;9(4):1030-3.
Pae M, Ren Z, Meydani M, Shang F, Meydani SN, Wu D. Epigallocatechin-3-gallate directly suppresses T cell proliferation through impaired IL-2 utilization and cell cycle progression. J Nutr. 2010 Aug;140(8):1509-15.