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Ernst J. Schaefer, M.D.

Ernst J. Schaefer Senior Scientist and Director
Lipid Metabolism Laboratory
Jean Mayer USDA HNRCA at Tufts University
711 Washington Street
Boston, MA 02111-1524
Phone: (617) 556-3100
Fax: (617) 556-3103
E-mail: ernst.schaefer@tufts.edu
Education B.M.S., Dartmouth Medical School
M.D., Mount Sinai School of Medicine
Research Focus Nutrition, genetics, lipoproteins, and cardiovascular disease risk
Academic Appointments Professor, Medicine, Tufts University School of Medicine
Professor, Gerald J. and Dorothy R. Friedman School of Nutrition Science and Policy at Tufts University
Director, Lipid and Heart Disease Prevention Clinic and Lipid Research Laboratory, New England Medical Center
Selected Professional Affiliations U.S. Editor, Atherosclerosis
Fellow, American Society of Clinical Nutrition
Board Certification Internal Medicine
Recent Publications

Thongtang N, Ai M, Otokozawa S, Himbergen TV, Asztalos BF, Nakajima K, Stein E, Jones PH, Schaefer EJ. Effects of maximal atorvastatin and rosuvastatin treatment on markers of glucose homeostasis and inflammation. Am J Cardiol. 2011; 107(3):387-92

Lamon-Fava S, Marcovina SM, Albers JJ, Kennedy H, Deluca C, White CC, Cupples LA, McNamara JR, Seman LJ, Bongard V, Schaefer EJ. Lipoprotein(a) levels, isoforms, and coronary heart disease risk In the Framingham Offspring Study. J Lipid Res. 2011 Jun;52(6):1181-7

van Himbergen T Otokozawa S, Matthan NR, Schaefer EJ, Buchsbaum A, Ai M, van Tits LJH, de Graaf J, Stalenhoef A. Familial combined hyperlipidemia is associated with alterations in the cholesterol synthesis pathway. Arterioscler Thromb Vasc Biol; 2010; 30:1113-20

Corcoran M, Meydani M, Lichtenstein AH, Schaefer EJ, Dillard A, Lamon-Fava S. Sex hormone modulation of proinflammatory cytokine and CRP expression in macrophages from old men and postmenopausal women. J Endocrinol 2010; 206:217-24

Polisecki E, Peter I, Simon J, Hegele RA, Robertson M, Ford I, Shepherd J, Packard C, Jukema JW, deCraen AJM, Westendorp RGJ, Buckley BM, Schaefer EJ. Genetic variation at the NPC1L1 gene locus, plasma lipoproteins, and heart disease risk in the elderly. J Lipid Res 2010; 51:1201-7

Ai M, Otokozawa S, Asztalos BF, Ito Y, Nakajima K, White CC, Cupples LA, Wilson PW, Schaefer EJ. Small dense low density lipoprotein cholesterol and coronary heart disease: results from the Framingham Offspring Study. Clin Chem 2010; 56:967-76

Schaefer EJ. ed High Density Lipoproteins, Dyslipidemia, and Coronary Heart Dusease, Springer Publishing, New York, 2010; pp 1-221. (book)

Asztalos BF, Swarbrick MM, Schaefer EJ, Dallal GE, Horvath KV, Ai M, Stanhope KL, Austrheim-Smith J, Wolfe BM, Ali M, Havel PJ. Effects of weight loss, induced by gastric bypass surgery, on HDL remodeling in obese women. J Lipid Res 2010;51:2405-12

Lamon-Fava S, Herrington DM, Horvath KV, Schaefer EJ, Asztalos BF. Effect of hormone replacement therapy on plasma lipoprotein levels and coronary atherosclerosis progression in postmenopausal women according to type 2 diabetes status. Metabolism 2010 Dec;59(12):1794-800

Schaefer EJ, Santos RD, Asztalos BF. Marked HDL deficiency and premature coronary heart disease. Curr Opin Lipidol 2010;21:289-97

Otokozawa S, Ai, M, Asztalos BF, White CC, Demissie-Banjaw S, Cupples LA, Nakajima K, Wilson PW, Schaefer EJ. Direct assessment of plasma low density lipoprotein and high density lipoprotein cholesterol. Atherosclerosis 2010; 213;:251-5.

Peloso GM, Demissie S, Collins D, Mirel DB, Gabriel SB, Cupples LA, Robins SJ, Schaefer EJ, Brousseau ME. Common genetic variation in multiple metabolic pathways influences susceptibility to low HDL-cholesterol and coronary heart disease. J Lipid Res. 2010;51:3524-32

Schaefer EJ, Gleason JA, Dansinger ML. Dietary fructose and glucose differentially affect lipid and glucose homeostasis. J Nutrition 2009;139:1257S-1262S

Lamon-Fava S, Herrington DM, Reboussin DM, Sherman M, Horvath K, Schaefer EJ, Asztalos BF. Changes in remnants and high density lipoproteins associated with hormonal therapy and progression of coronary artery disease in post-menopausal women. Atherosclerosis 2009;205:325-330

Otokozawa S, Ai M, Diffenderfer M, Asztalos BF, Lamon-Fava S, Schaefer EJ. Fasting and post-prandial apolipoprotein B-48 levels in healthy, obese, and hyperlipidemic subjects. Metabolism 2009; 58: 1536-42.