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Global
Research to Improve Antimicrobial Policy and Practice (GRIP) Program.
(Formerly known as the Small Grants Program)
APUA
international chapters form a global network of healthcare practitioners
and scientific groups working on antibiotic resistance in various locales
around the world. Chapters serve as a source of resistance information
and as a vehicle to tailor the prudent use message to local customs
and medical practices. To foster their work, APUA has initiated a small
grants program that will provide seed money of up to $3000 for short-term
research and research-based educational activities designed to curb
antibiotic resistance and promote the prudent use of antibiotics.
Projects are evaluated according to their research plans and their potential
to improve policy and practice. At this time, only APUA chapters from
developing and transitional countries are eligible to apply for support
through the small grants program. Thus far, chapters in Belarus, Brazil,
Bulgaria, Columbia, Cuba, Guatemala, India, Moldova, Nepal, Peru, Poland,
Russia, Ukraine, Uruguay and Vietnam have been awarded grants for research
projects, such as a study on antimicrobial prescribing in children with
respiratory tract infections, a conference on rational antibiotic use
for healthcare professionals and students, and surveillance of antimicrobial
resistance.
Current funded research is in response to a 2001 Request for Proposals
entitled Cost Analyses of Antibiotic Usage Patterns: impact of antibiotic
control measures. The following chart highlights the impacts of
current grantees’ work.
| Country |
Title
of Project |
Principal
Investigator |
Impacts
of Project on Policy and Practice to Date |
| Moldova |
"Analysis
of the Sale and Dispensing of Antibiotics in Moldova" |
Dr.
Natalia Cebotarenco |
- Provided
trended data about antimicrobial consumption from 5 hospitals
and 3 Children’s Emergency Rooms in Moldova in 1991 and 2001,
a necessary underpinning of good antimicrobial policy.
- Educated
physicians about trends in antibiotic use from 1991 to 2001
with the aim of promoting rational use of antimicrobials.
|
| Nepal
|
"Development
of National Antibiotic Guidelines in Nepal." |
Dr.
Shyam P. Lohani |
- Drafted
national antibiotic guidelines for Nepal, with input from key
stakeholders, which were submitted to the Nepal Ministry of
Health for implementation.
|
| Peru |
"Determining
the Economic Impact of Surgical Site Infections at Hospital Nacional
Cayetano Heredia in Lima, Peru" |
Dr.
Dalila Y. Martínez Medina |
- Taught
surgery staff how to perform active surveillance for surgical
site infections (SSI) at the Hospital Nacional Cayetano Heredia.
- Discovered
that extended hospitalizations, extra cleaning procedures, and
re-surgery for patients with SSIs occurred at double the rate
of patients without these infections.
- Instituted
a policy of accelerated discharge based on findings that 15%
of patients develop a second SSI when they stay longer than
necessary in the hospital.
|
| Poland |
"Cost-Effectiveness
of Evolving Antibiotic Prescribing in Primary Care Hospitals in
Poland." |
Dr.
Pawel Grzesiowski and Dr. Waleria Hryniewicz |
- Updated
selected guidelines for diagnosis, prevention, and treatment
of respiratory tract infections.
- Developed
forms for physician use in reporting antimicrobial consumption
for treatment and prophylaxis.
|
| Russia |
"Cost-Effectiveness
Analysis of MiniVITAL Automated System (Biomerieus) Vs. Routine
Microbiological Procedures for Blood Cultures from ICU Patients
with Sepsis in Russian Hospitals." |
Prof.
L.S. Stratchounski |
- Study
results will help hospitals decide how to most cost-effectively
culture ICU patients with sepsis.
|
| Ukraine |
"Estimation
of the Economic Impact of Inappropriate Microbiological Sample Culturing
in a Ukrainian City Hospital." |
Dr.
Igor Bereznyakov |
- Determined
the cost of inappropriate or inadequate microbiological sample
culturing in the Kharkiv City Hospital Microbiology Laboratory.
- Developed
a microbiological training program for Kharkiv City Hospital
doctors and nurses.
- Presented
preliminary study results at the APUA-Ukraine Conference on
Clinical Microbiology and Antimicrobial Chemotherapy in February
2003.
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| Uruguay |
"Cost
of Staphylococcus aureus hospital acquired infections: implications
of methicillin-resistant and methicillin-susceptible isolates in
University Hospital in Montevideo, Uruguay" |
Dr.Rosario
Palacio |
- Established
a baseline estimate of methicillin-resistant Staphylococcus
aureus (MRSA) at University Hospital in Montevideo
- Engaged
hospital decision makers in discussions of the cost and policy
implications of MRSA.
- Provided
data about the clinical and economic characteristics of MRSA
at University Hospital.
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APUA
is currently seeking dedicated funding to support the GRIP Program. Pursuant
to chapter interest, the next round of GRIP-funded research programs will
focus on the relationship between antibiotic use and resistance.
For more information on this program, please
contact
us.
Return
to APUA Chapters webpage.
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