The Tufts University Biological NMR Center (TBNMRC) has 3 Bruker NMR Spectrometers housed in it's facility. A Bruker Avance DRX-600, Bruker AMX-500 and a Bruker Avance DPX-300. All equiped for demanding multidimensional, multinuclear spectroscopic applications.

For information on each NMR Spectrometer:

Avance DRX-600 - AMX-500 - Avance DPX-300

For information on Bruker NMR Spectrometers: http://www.bruker.com

The Facility has 4 separate off-line computers for data processing and modeling of protein structures. All Silicon Graphics (SGI) workstations (O2, INDY and INDIGO) running either UNIX or the IRIX OS connected to H/P Laserjet 8000 with 16Mb memory, and Epson 1520 Color Inkjet Plotter, running ESP software driver.

All optimized for applications (licensed by the facility) such as FELIX and INSIGHT from Biosym/MSI - both are used for NMR data processing and molecular modeling respectively. Additional software includes PRONTO - a tool for protein sequential assignment, STEREOSEARCH - for determination of stereospecific assignments and backbone torsion angles, CORMA - for iterative refinement of distance restraints using the complex relaxation matrix, X-PLOR - for protein structure determination by distance geomtery and/or simulated annealing, BIBBONS and MOLSCRIPT - for graphical representation of biomolecular structures, GRASP - a program for generation and display of electrostatic potential surfaces, and TRIAD, SYBYL & BIOPOLYMER from TRIPOS - are NMR processing and assignment tools, molecular modeling (including homology search and docking modules), and molecular building programs respectively.

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