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Research Areas:
click
the links
below to learn
more.
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The research
interests of the Faculty
cover a wide variety of specialties in many areas of basic biomedical
research. Being located at Tufts Medical School with close ties to
the Tufts New England Medical Center, all the research interests of our
program
members are disease related. Below, the research
specialties
of the faculty are grouped both according to their field in Basic
Biomedical Research and Disease Related Research.
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Basic Biomedical Research:
Structural Biology:
Cell Signaling
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Amy
S. Yee
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Transcriptional
regulation in response to cell growth and
differentiation signals |
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Larry
A. Feig
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Ras signaling in the control of
cell proliferation, calcium signaling
in neurons |
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Brian
Schaffhausen |
Mechanism
of neoplastic transformation, signal transduction |
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Athan
Kuliopulos
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Signaling of
protease activated receptors (PARs) |
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Akiko
Hata
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Regulation of cell growth and
development |
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Eric
Paulson
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Reactive Oxygen Species Signaling
in Mitogenesis and
Tumorigenesis |
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Jim
Baleja |
The regulation of cellular location
of signaling proteins
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Michael
Forgac
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pH control of intracellular
compartments in eukaryotes
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Philip Hinds |
The retinoblastoma
protein pathway in differentiation, senesence and cancer |
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Michael
Mendelsohn
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Molecular signaling mechanisms in
vascular biology |
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back
to the top |
Replication and Regulation of Gene
Expression
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Peter
Bullock
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Initiation of DNA replication and
the control of this process
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Akiko
Hata
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Transcriptional Regulation of
growth factors |
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Gavin
Schnitzler
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Function of
human chromatin remodeling complexes in transcriptional control. |
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Andrew Bohm |
Structural basis for processing and
polyadenylation of
messenger RNA
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Brian
Schaffhausen |
Mechanism
of neoplastic transformation |
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Amy
Yee
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Transcriptional regulation in
response to cell growth and
differentiation signals |
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Claire
L. Moore
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mRNA processing and its role in the
regulation of gene expression
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Philip Hinds
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The retinoblastoma
protein pathway in differentiation, senesence and cancer |
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to the top |
Drug
Design and Medicinal Chemistry
Disease Related Research
Cancer
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Brian
Schaffhausen |
Mechanism
of neoplastic transformation |
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Amy
Yee |
Transcriptional
regulation in response to cell growth and
differentiation signals |
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Eric
Paulson |
Reactive Oxygen Species (ROS)
Signaling in Mitogenesis and
Tumorigenesis |
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Larry
Feig |
How Ras proteins contribute to
oncogenesis, Ras-GTPases in breast cancer |
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Gavin
Schnitzler |
Function of
human chromatin remodeling complexes in transcriptional control |
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Jim
Baleja |
Cervical dysplasia and cancer |
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Peter
Bullock |
Role of DNA replication as it
pertains to cell cycle regulation and DNA repair
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Philip Hinds |
The retinoblastoma
protein pathway in differentiation, senesence and cancer |
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back to the
top |
Infectious
Disease
Cardiovascular Disease
Diabetes
Autoimmune and Inflammatory Disease
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