Resources

The Sackler Building
 houses the Library,
various administrative offices, and two
large lecture halls.

Library Resources

Laboratories & Physical Layout

Facilities & Major Equipment

Other Tufts Facilities & Equipment

Computer Resources

Library Resources

Laboratories & physical layout.

Biochemistry department labs are located on the 6th floor of the Jaharis and M&V buildings and on the 7th floor of the Stearns and Arnold buildings.  The labs in all four buildings are at the same elevation, and the buildings are connected to one another so as to facilitate communication between laboratories and sharing of equipment.

The biochemistry space houses the administrative staff, a small library, and rooms dedicated to crystallography and NMR.  In addition, there are three cold rooms, a warm room, a tissue culture room, and two meeting/lecture rooms.

Large lectures are held either across the street in the Sackler building (which also houses the Tufts Medical Sciences Library) or on the first floor of the Jaharis building.

Facilities

Nuclear Magnetic Resonance:  Dr Bill Bachovchin directs the NMR center. 

The center houses three spectrometers equipped for multidimensional, multinuclear spectroscopic applications; a Bruker Avance DRX-600, a Bruker AMX-500 and a Bruker Avance DPX-300. Dr. James Sudmeier and Dr. David Sanford are responsible for training new users and maintaining the magnets and related computer facilities.

X-Ray Crystallography:  Dr. Bohm oversees the X-ray diffraction system.  The setup includes a 2Kx2K 165 mm front face CCD camera (Oxford Diffraction) and is equipped with a cryo-cooling unit.  Computers running various crystallographic software packages are located in the Bohm laboratory.

Isothermal Titration Calorimetry: A microcal ITC instrument is located in Dr. Baleja's laboratory.

Mass Spectrometers: David Sanford oversees the Thermo Finnigan LCQ DUO ESI trap and Agilent 1100 series LCD/MSD trap mass spec instruments.

Fluorescence Spectrophotometer: Dr. Baleja oversees the Fluorolog Fluorescence Spectrophotometer.

Circular Dichroism Spectrophotometer: Dr. Baleja oversees a JASCO 810 circular dichroism spectropolarimeter which is located Room MV605B.

Fermenter: A BioFlow 2000 fermentor is available for large scale bacterial growth.  You must contact Dr. Bohm for more information before using this instrument.

Shakers are scattered throughout the department in various labs.

Centrifuges & Rotors: A number of centrifuges including large and small ultracentrifuges, and lower speed instruments are scattered throughout the department.  Dr. Schnitzler oversees many of these instruments.

Chromatography: Most labs maintain their own HPLC and/or FPLC-type systems.  There is also a shared pharmacia FPLC system in one of the cold rooms.

Other Facilities & Equipment

8th floor of Stearns.
DNA sequencing, DNA synthesis, Peptide sequencing, Peptide synthesis, Mass Spectrometry Analysis and Proteomic HPLC / MS with Nanospray

Confocal microscopy and digital image analysis

M&V 504
Transmission and scanning electron microscopes

M&V 523
Gene microarray facility, bioinformatics analysis

Physical mapping and ordering genomic DNA or cDNA sequences

Tupper 11
includes equipment and expert technical capability for performing experiments

analysis of gene expression data

Computer Resources

Tufts computing and communications services handles routine Internet connectivity and e-mail issues and manages the academic computing cluster.

A cluster of 32 dual processor Linux machines is available for computationally intensive research applications (ie. ligand docking applications and molecular dynamics simulations)