There are five areas of study: a) The E. coli marRAB (multiple antibiotic resistance) operon in which marR codes for an autorepressor of the operon and marA codes for a regulator protein which activates the transcription of many other genes, leading to multiple antibiotic resistance; b) The Tn10-encoded tetracycline efflux protein TetA(B), a membrane transport protein which causes tetracycline resistance in bacteria by pumping out the antibiotic; c) Multidrug (mdr) resistance in cultured mammalian cells; d) Genes important for the colonization of pseudomonads in soil; e) Impact on bacterial antibiotic resistance of household use of surface antibacterials.

See more information about the Levy Lab at The Center for Adaptation Genetics and Drug Resistance.