Levy Laboratory [Faculty & Research]

Adaptation Genetics and Drug Resistance

Principal Investigator
Stuart Levy
Professor
 
Contact Information
Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111
Office (617) 636-6764
Lab (617) 636-6765
Fax (617) 636-0337
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Bina, X., V. Perreten and S.B. Levy. (2003). The periplasmic protein MppA requires an additional mutated locus to repress marA expression in Escherichia coli. J. Bacteriol. 185:1465-1469.
Robleto, E.A., I. Lopez-Hernandez, M.W. Silby and S.B. Levy. (2003) Genetic analysis of the AdnA regulon in Pseudomonas fluorescens: non-essential role of flagella in adhesion to sand and biofilm formation. J. Bacteriol. 185:453-460.
McMurry, L.M. and S.B. Levy. (2002) Fe2+ -Tetracycline-Mediated Cleavage of the Tn10 Tetracycline Efflux Protein TetA Reveals a Substrate Binding Site near Glutamine 225 in a Transmembrane Helix 7. J. Bacteriol. 184:5113-5120.
Barbosa, T.M. and S.B. Levy. (2002) Activation of the Escherichia coli nfnB gene by MarA through a highly divergent marbox in a class II promoter. Molec. Microbiol. 45(1):191-202.
Alekshun, M.N., S.B. Levy, T.R. Mealy, B.A. Seaton, and J.F. Head. (2001) The crystal structure of MarR a regulator of multiple antibiotic resistance, at 2.3A resolution Nature Structural Biology 8: 710-714.
Wang, H., J.L. Dzink-Fox, M. Chen, and S.B. Levy. (2001) Genetic characterization of high-level fluoroquinolone resistant clinical Eschericahia coli strains from China: role for acrR mutations. Antimicrob. Agnts. Chemother. 45: 1515-1521.
Marshall, B., E. Robleto, R. Wexler, P. Casaz and S.B. Levy. (2001) The AdnA transcriptional factor affects persistence and spread of Pseudomonas fluorescens under natural field conditions. Appl. Env. Microb. 67: 852-857.
Casaz, P., A. Happel, J. Keithan, D. Read, S. Strain and S.B. Levy. (2001) The Pseudomonas fluorescens transcriptional activator AdnA is required for adhesion and motility. Microbiology 147: 355-361.
Saraceni-Richards, C. and S.B. Levy. (2000) Second site suppressor mutations of Gly-247 substitution mutants of the tetracycline efflux protein Tet(B) J. Bacteriol. 182: 6514- 6516.
Yin, C-C., M.L. Aldema-Ramos, I. Borges-Walmsley, R.W. Taylor, A.R. Walmsley, S.B. Levy and P.A. Bullough. (2000) The quarternary molecular architecture of TetA, a secondary tetracycline transporter from Escherichia coli Molec. Microb. 38: 482-492.
Wong, Rebecca S.Y., L.M. McMurry and S.B. Levy (2000) “Intergenic” blr gene in Escherichia coli encodes a 41 residue membrane proein affecting intrinsic susceptibility to certain inhibitors of peptidoglycan synthesis. Molec. Microbiol. 37: 364-370.
Barbosa, T. and S.B. Levy. (2000) Differential expression of over 60 chromosomal genes in Escherichia coli by constitutive expression of MarA. J. Bacteriol. 182: 3467-3474.
Kern, W.V., M. Oethinger, A.S. Jellen-Ritter and S.B. Levy (2000) Non-target gene mutations in the development of fluoroquinolone resistance in Escherichia coli. Antimicrob. Agts. Chemother. 44:814-820.
Alekshun, M.N., Y.S. Kim and S.B. Levy (2000) Mutational analysis of MarR, the negative regulator of marRAB expression in Escherichia coli, suggests the presence of two regions required for DNA binding. Molec. Microbiol. 35:1394-1404.
Saraceni-Richards, C. and S.B. Levy (2000) Evidence for interactions between helices 5 and 8 and a role for the interdomain loop in tetracycline resistance mediated by hybrid Tet proteins. J. Biol. Chem 275:6101-6106.

 

 

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