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Faculty Profile: Surendra P. Verma, Ph.D.
| Research Associate
Professor
Department of Public Health and Family Medicine
Tufts University School of Medicine
Tufts University School of Medicine
150 Harrison Ave., Jaharis 3
Boston, MA 02111
| Phone: |
617-636-0814 |
| Fax: |
617-636-3810 |
| E-mail: |
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| Education |
Ph.D., Physical Biochemistry
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| Research Focus |
Effects of environmental pollutants on the
growth of breast tumor cells and effects of dietary compounds
on the pollutant-induced growth of breast tumor cells; isoflavone-induced
activation of nitric oxide synthases in breast tumor cells and
nitric oxide-induced signal transduction pathways in tumor cells;
effects of other dietary compounds (e.g., curcumin) and copper
including other trace metal ions on the activities of nitric
oxide synthases in breast tumor cells. Biospectroscopic structural
studies of membranes, protein/enzymes, lipids, LDL, lipoproteins
and carotenoids and detection of abnormal proteins in samples
prepared from neoplastic cells and in plasma from patients having
(i) cancer, (ii) diabetes and muscular dystrophy using Raman
spectroscopy. |
| Selected Publications |
- US PATENT # 4,832,483: Method
of using Resonance Raman Spectroscopy for detection of malignancy
disease using human plasma.
- Verma SP, Goldin BR, Lin PS.
The inhibition of the estrogenic effects of pesticides and
environmental chemicals by curcumin and isoflavonoids. Environ
Health Perspect 1998;106:807-812.
- Verma SP and Goldin BR. Effect
of soy-derived isoflavonoids on the induced growth of MCF-7
cells by estrogenic environmental chemicals. Nutr &
Cancer 1998;30:232-239.
- Verma SP and Goldin BR Letter
to the Editor. N Eng J Med 1998;990.
- Verma SP, Salamone E, Goldin
BR. Curcumin and genistein, plant natural products, show
synergistic inhibitory effects on the growth of human breast
cancer MCF-7 cells induced by estrogenic pesticides. Biochem
Biophys Res Com 1997;233:692-696.
- Khulbe KC, Kruczek B, Chowdhary G, Gagne S, Matsuura
T, Verma SP. Characterization
of membrane prepared for poly (2-6 dimethyl oxide) by Raman
scattering and Atomic Force Microscope. J Membrane Sci 1996;111:57-70.
- Verma SP and Goldner RB. Raman
spectroscopic evidence for structural changes ploy-L-lysine
induced by an approximately 50mT static magnetic field.
Bioelectrogmaetics 1996;17:33-36.
- Verma SP, Singhal A, Sonwalkar
N. Ionizing radiation target groups of band 3 inserted into
egg lecithin liposomes as determined by Raman spectroscopy.
Int J Radiat Biol 1993;63,:279-288.
- Verma SP, Rastogi A, Lin PS.
Hexachlorocyclohexane pesticides reduce survival and alter
plasma membrane structure of Chinese hamster V79 cells.
Arch Biochem Biophys 1992;298:587-93.
- Verma SP and Singhal A. Low
levels of the pesticide, Delta Hexachlorocyclo-hexane, lyses
human erythrocytes and alters the organization of membrane
lipids and proteins as revealed by laser Raman spectroscopy.
Biochem Biophys Acta 1991
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