Principal Investigator:
John Castellot, Ph.D.
Professor and Director of the CMDB Graduate Program
Department of Anatomy and Cellular Biology

Department of Anatomy & Cellular Biology
Tufts University 
School of Medicine
136 Harrison Avenue
Boston, Massachusetts 02111

Office Phone:  
(617)636-0303
Lab Phone: 
(617)636-
FAX: 
(617)636-6536

EMail Address:
john.castellot@tufts.edu


Program in Cellular and Molecular Biology

Sackler School

Medical School

Fig. 14 CCN5 expression is correlated with high estrogen levels in women. Using matched pairs of human fibroid and normal myometrium, we measured CCN5 protein levels using Western blot analysis as a function of menstrual cycle phase. The highest levels of CCN5 are found in proliferative phase, when estrogen levels are highest, whereas the lowest levels of CCN5 are found in the menstrual phase, when estrogen levels are lowest.