Principal Investigator:
John Castellot, Ph.D.
Professor and Director of the CMDB Graduate Program
Department of Anatomy and Cellular Biology

Department of Anatomy & Cellular Biology
Tufts University 
School of Medicine
136 Harrison Avenue
Boston, Massachusetts 02111

Office Phone:  
(617)636-0303
Lab Phone: 
(617)636-
FAX: 
(617)636-6536

EMail Address:
john.castellot@tufts.edu


Program in Cellular and Molecular Biology

Sackler School

Medical School

Fig. 4 Heparin inhibits restenosis. Heparin, a complex carbohydrate, is capable of reducing restenosis following balloon angioplasty in the rat. The IEL in both untreated controls and animals treated with heparin are lined up and marked with arrows. Untreated controls show massive SMC hyperproliferation after 14 days as expected, whereas heparin-treated animals have far less restenosis.