Lab Home Coworkers and Collaborators Selected Publications Research Expertise



Principal Investigator:
Jake (Jinkun) Chen, DDS, Ph.D. Professor

Dr. Chen

DDS, Shanghai Second Medical University, 1982

M. Dent. Sci. and Oral Pathology Certificate, University of Connecticut, 1988

Ph.D., University of Toronto, Canada, 1992

Department of General Dentistry

Department of Anatomy and Cell Biology

Department of Anatomy & Cellular Biology
Tufts University 
School of Medicine
136 Harrison Avenue
Boston, Massachusetts 02111

Phone:   617-636-2729

FAX: 

EMail Address:
JK.Chen@tufts.edu

Program in Cellular and Molecular Biology

Sackler School

Medical School

 

 

Selected Publications

Selected Publications in 2008:

Zhang J, Zhu J, Valverde P, Li L, Pageau S, Tu Q, Nishimura R, Yoneda T, Yang P, Zheng W, Ma W, Chen J.  Phenotypic analysis of Dlx5 overexpression in post-natal bone.  J Dent Res 87:45-50, 2008.

Li S, Tu Q, Zhang J, Stein G, Lian J, Yang PS, Chen J.  Systemically transplanted bone marrow stromal cells contributing to bone tissue regeneration.  J Cell Physiol. 215:204-9, 2008.

Valverde P, Zhang J, Fix A, Zhu J, Ma W, Tu Q, Chen J.  Overexpression of Bone Sialoprotein Leads to an Uncoupling of Bone Formation and Bone Resorption in Mice.  J Bone Miner Res. 2008 Jul 2. [Epub ahead of print]

Tu Q, Zhang J, Paz J, Wade K, Yang P, Chen J.  Haploinsufficiency of Runx2 results in bone formation decrease and different BSP expression pattern changes in two transgenic mouse models.  J Cell Physiol. 217:40-7, 2008.

Zhao Y, Wang C, Li S, Song H, Wei F, Pan K, Zhu K, Yang P, Tu Q, Chen J.  Expression of Osterix in mechanical stress-induced osteogenic differentiation of periodontal ligament cells in vitro. Eur J Oral Sci. 116(3):199-206, 2008.

Tu Q, Zhang J, Fix A, Brewer E, Li YP, Zhang ZY, Chen J.  Targeted overexpression of BSP in osteoclasts promotes bone metastasis of breast cancer cells.  J Cell Physiol. 2008 Aug 28. [Epub ahead of print]

Zhang J, Tu Q, Pageau S, Tang J and Chen J. Establishment of an Animal Model for Bisphosphonates-Associated ONJ to Investigate the Roles of Zoledronic Acid in Bone Healing and Osteoblast Functions. Submitted, 2008.

Xu B, Zhang J, Brewer E, Tu Q, Wieland M, Yu L and Chen J. Bone Marrow Stromal Cells and Osterix Contributing to Osseointegration of Dental Implants.  Submitted, 2008.

Xu P, Zhang J, Liu H, Will L, Chapman RJ and Chen J. Evaluation of a Combined Prosth-Orthodontic Treatment for Maxillary Protrusion in Middle-Aged Adults. Submitted, 2008.

Zhang J, Tu Q and Chen J.  Applications of Transgenics in studies of BSP.  Submitted, 2008


 


 

Program in Cell, Molecular, and Developmental Biology
136 Harrison Avenue, 5th Floor
Boston, MA 02111 617-636-6685

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