Principal Investigator:
Jake (Jinkun) Chen, DDS, Ph.D. Professor



DDS, Shanghai Second Medical University, 1982

M. Dent. Sci. and Oral Pathology Certificate, University of Connecticut, 1988

Ph.D., University of Toronto, Canada, 1992

Department of General Dentistry

Department of Anatomy and Cell Biology

Department of Anatomy & Cellular Biology
Tufts University 
School of Medicine
136 Harrison Avenue
Boston, Massachusetts 02111

Phone:   617-636-2729

FAX: 

EMail Address:
JK.Chen@tufts.edu

Program in Cellular and Molecular Biology

Sackler School

Medical School

Cell Biology
Developmental Biology
Tumor Biology

Gene expression and regulation of extracellular matrix proteins;
Bone formation related to periodontal regeneration and tissue engineering;
Non-collagenous proteins regulated by transcription factors and hormones;
Benign bone lesions and bone tumor in the jaws;
Transgenic mouse study of bone sialoprotein.

Other Interests:

Osteopontin and BSP in malignancy and bone metastasis;
Smokeless tobacco and oral cancer.

Laboratory Expertise:

Recombinant DNA techniques
Transgenic techniques
PCR techniques
Animal surgery
Retroviral receptor in transgenics
Histopathology
In situ hybridization
Immunohistochemistry
Carcinogenesis
Cell and tissue cultures