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The Graduate Program in Cell, Molecular,and Developmental
Biology (CMDB) provides an administrative and intellectual
structure to support rigorous training of pre-doctoral
and postdoctoral fellows in the study of molecular mechanisms
of cell, tissue and organ function. These goals are accomplished
within an interactive environment inwhich faculty and
students participate in seminar series, journal clubs,
joint lab meetings, and an annual retreat. The Ph.D. includes
coursework in Cell Biology, Developmental Biology, Molecular
Biology, Genetics and Biochemistry.
Research
efforts in the Program focus on mechanisms of cell proliferation
and tumor metastasis; of development and differentiation;
and of signal transduction. Individual projects deal with
extra-cellular matrix assembly, turnover and functions
in cell behavior and disease; vascular cell development
and function; smooth and skeletal muscle structure and
differentiation; mechanisms of reproductive hormone action
and of xenobiotic action; gametogenesis and fertilization;
mechanisms of division in mitotic and meiotic cells; cellular
and molecular mechanisms underlying neoplasia and metastasis;
cellular and genetic aspects of neurobiology.
The
Program has access to a range of Core Facilities that
aid faculty and students. These include the: (i) Gene
Microarray Facility, (ii) Protein and DNA Sequencing Facility;
(iii) Flow Cytometry Facility; (iv) Molecular Probe and
Assay Core Facility; (v)< Core Imaging> ; (vi) Electron
Microscopy Facility; (vii) Confocal Microscopy Facility
and Digital Image Analysis Facility.
These facilities supplement state-of-the-art biochemical,
biophysical, molecular and morphological techniques that
are utilized by members of the Program. Finally, the Program
is housed within the Health Sciences Campus of Tufts University,
permitting students and faculty to interact with a wide
range of colleagues at Tufts University School of Medicine
and our affiliated hospitals.
Pre-doctoral
studies within the Program are supported by a training
grant from the National Institutes of Health. Ph.D. candidates
are encouraged to communicate with us directly through
this Web site. Please note that predoctoral students wishing
to enter the CMDB Program must do so through the Integrated
Studies Program, a combined admissions and first-year
academic program that serves as the portal of entry for
three Sackler School Ph.D. programs: CMDB, Cellular and
Molecular Physiology, and Biochemistry.Those interested
in postdoctoral training should contact individual faculty
members.
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