Principal Investigator:
Grace Gill, Ph.D.


Department of Anatomy & Cellular Biology
Tufts University 
School of Medicine
136 Harrison Avenue
Boston, Massachusetts 02111

Office Phone:  
(617)636-3757
Lab Phone: 
(617)636-3923
FAX: 
(617)636-6536

EMail Address: Grace.Gill@tufts.edu

Program in Cell, Molecular and Developmental Biology

Graduate Program in Genetics

Sackler School of Graduate Biomedical Sciences

Dental School

Sackler School

Medical School

Ross, S., Tienhaara, A., Lee, M.-S., Tsai, L.-H., and Gill, G. (2002) GC box-binding transcription factors control the neuronal specific expression of the cdk5 regulator p35. J. Biol. Chem 277: 4455-4464.

Ross, S., Best, J.L., Zon, L., and Gill, G. (2002) SUMO-1 modification represses Sp3 transcriptional activation and modulates its subnuclear localization. Molecular Cell 10: 831-842.

Gill, G. (2003) Post-translational modification by the small ubiquitin related modifier SUMO has big effects on transcription factor activity. Current Opinions in Genes and Development 13:108-113.

Di Bacco A. and Gill, G. (2003) The secreted glycoprotein CREG inhibits cell growth dependent on the mannose-6-phosphate/insulin-like growth factor II receptor. Oncogene 22: 5436-5445.

Hemelaar J. , Borodovsky A., Kessler B.M., David Reverter D., Cook,J., Kolli, N. Gan-Erdene T., Wilkinson, K.D., Gill, G., Lima C.D.,. Ploegh H.L., and Ovaa, H. (2004) Specific and covalent targeting of conjugating and deconjugating enzymes of ubiquitin-like proteins. Mol. Cell Biol. 24: 84-95.

Gill,G. (2004) SUMO and ubiquitin in the nucleus: different functions, similar mechanisms? Genes and Dev. 18: 2046-2059.

Sacher, M., Di Bacco, A., Lunin, V., Ye,Z., Wagner, J., Gill, G., and Cygler,M. (2005) The structure of CREG, a secreted glycoprotein involved in cellular growth and differentiation. Proc. Nat. Acad. of Sciences 102: 18326-18331.

Gill, G. Something about SUMO inhibits transcription. (2005) Current Opinions in Genes and Development 15: 536-541.

Rosendorff,A., Sakakibara,S., Lu,S., Kieff,E., Xuan,Y., DiBacco, A., Shi, Y., Shi, Y., and Gill, G. (2006) NXP-2 association with SUMO-2 depends on lysines required for transcriptional repression. Proc. Nat. Acad. of Sciences, 2006; 103, 5308-5313.

Di Bacco A., Ouyang, J., Lee, H.-S., Catic, A. Ploegh, H., and Gill, G. (2006) The SUMO-specific protease SENP5 is required for cell division. Mol. Cell Biol. 26, 4489-4498.

Di Bacco, A., and Gill, G (2006) SUMO-specific proteases and the cell cycle : An essential role for SENP5 in cell proliferation. Cell Cycle 5: 2310-2313.

Ramos, B., Gaudilliere, B., Bonni, A., and Gill, G. The transcription factor Sp4 regulates dendritic patterning during cerebellar development. Manuscript submitted.

Program in Cell, Molecular, and Developmental Biology 136 Harrison Avenue, 5th Floor Boston, MA 02111 617-636-6685 Questions and comments to: Web Development page last modified 4/30/07