| Selected
Publications Eller,
M.S. and Sarkar, S. 1989. Myosin Light Chain 3 Synthesis during
Chick Pectoralis Muscle Development In Ovo. Dev. Biol., 136:284-286.
Eller, M., Stedman, H.H., Sylvester, J.E., Fertels, S.H., Wu, Q-L.,
Raychowdhury, M.K., Rubinstein, N.A., Kelly, A.M. and Sarkar, S.
1989. Human Embryonic Myosin Heavy Chain cDNA: Interspecies Sequence
Conservation of the Myosin Rod, Chromosomal Locus and isoform Specific
Transcription of the Gene. FEBS Lett., 256:21-28.
Wu, Q.-L., Jha, P.K., Raychowdhury, M.K., Du, Y., Leavis, P.C. and
Sarkar, S. 1994. Isolation and characterization of human fast skeletal
beta troponin T cDNA: Comparative sequence analysis of isoforms
and insight into the evolution of members of multigene family. DNA
and Cell Biology, 13:217-233.
Wu, Q-L., Jha, P.K., Du, Y., Leavis, P.C., and Sarkar, S. 1995.
Over production and rapid purification of human fast skeletal beta
troponin T using Escherichia coli expression vectors: Functional
differences between alpha and beta isoforms. Gene, 155:225-230.
Mao, C., Baumgartner, A.P., Jha, P.K., Huang, T. H.-M. and Sarkar,
S. 1996. Assignment of the human fast skeletal troponin T gene (TNNT3)
to chromosome 11p15.5: Evidence for the presence of 11pter in a
monochromosome 9 somatic cell hybrid in NIGMS mapping panel 2. Genomics,
31:385-388.
Jha, P.K., Mao, C. and Sarkar, S. 1996. Photocrosslinking of rabbit
skeletal troponin I deletion mutants with troponin C and its thiol
mutants: The inhibitory region enhances binding of troponin I fragments
to troponin C. Biochemistry 35:11026-11035.
Jha, P.K., Leavis, P.C., and Sarkar, S. 1996. Interaction of deletion
mutants of troponins I and T: COOH-terminal truncation of troponin
T abolishes troponin I binding and reduces Ca2+ sensitivity of the
reconstituted regulatory system. Biochemistry 35:16573-16580.
Stefancsik, R., Jha, P.K., and Sarkar, S. 1998. Identification and
mutagenesis of a highly conserved domain in troponin T responsible
for troponin I binding: Potential role for coiled coil interaction
Proc. Natl. Acad. Sci. 95:957-962.
Jha, P.K. and Sarkar, S. 1998. A recombinant monocysteine mutant
(ser to Cys-155) of fast skeletal troponin T: Identification by
cross-linking of a domain involved in a physiologically relevant
interaction with troponins C and I. Biochemistry 37:12253-12260.
Stefancsik, R. and Sarkar, S. 2003. Relationship between the DNA
binding domains of SMAD and NFI/CTF transcription factors defines
a new superfamily of genes. DNA Sequence 14: 233-239.
Sachdev, S., Raychowdhury, M.K., and Sarkar S. 2003. Human fast
skeletal myosin light chain 2 cDNA: isolation, tissue specific expression
of the single copy gene, comparative sequence analysis of isoforms
and evolutionary relationships. DNA Sequence 14: 339-350.
Stefancsik, R., Randall,
J.D., Mao, C-j., and Sarkar, S. 2003. Structure and sequence of
the human fast skeletal troponin T (tnnt3) gene: insight into the
evolution of the gene and the origin of the developmentally regulated
isoforms. Compartive and Functional Genomics 4: in press.
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