Principal Investigator:
Schwob, James, M.D., Ph.D.
George A. Bates Professor of Histology and Chair Department of Anatomy and Cellular Biology

Department of Anatomy & Cellular Biology
Tufts University 
School of Medicine
136 Harrison Avenue
Boston, Massachusetts 02111

Office Phone:  
(617)636-6626

Lab Phone: 
(617)636-2418

FAX: 
(617)636-0823

EMail Address: jim.schwob@tufts.edu

Program in Cellular and Molecular Biology

Sackler School

Medical School

Publications

Schwob, J.E., S.L. Youngentob and R.C. Mezza  1995  The reconstitution of the rat olfactory epithelium after methyl bromide-induced lesion.  J. Comp. Neurol.  359: 15-37. PubMed

Goldstein, B.J., and J.E. Schwob  1996  Analysis of the globose basal cell compartment in rat olfactory epithelium using GBC-1, a new monoclonal antibody against globose basal cells.  J. Neurosci. 16: 4005-4016. PubMed

Goldstein, B.J., B.L. Wolozin and J.E. Schwob  1997  FGF2 suppresses neuronogenesis by a cell line derived from rat olfactory epithelium.  J. Neurobiol.  33: 411-428. PubMed

Goldstein, B.J., H. Fang, S.L. Youngentob and J.E. Schwob  1998  Transplantation of multipotent progenitor cells from adult olfactory epithelium.  NeuroReport, 9: 1611-1617. PubMed

Huard, J.M.T., S.L. Youngentob, Goldstein, B.J. M.B. Luskin and J.E. Schwob  1998  Olfactory epithelium contains multipotent progenitors that give rise to neurons and non-neuronal cells.  J. Comp. Neurol., 400: 469-486. PubMed

Christensen, M., E.H. Holbrook, R.M. Costanzo and J.E. Schwob 2001 Rhinotopy is disrupted during the reinnervation of the olfactory bulb that follows transection of the olfactory nerve. Chem. Senses., 26: 359-369. PubMed

Schwob, J.E., S. Saha, S.L. Youngentob and B. Jubelt 2001 Intranasal inoculation with the olfactory bulb line variant of mouse hepatitis virus causes extensive destruction of the olfactory bulb and accelerated turnover of neurons in the olfactory epithelium of mice. Chem. Senses, 26: 937-952. PubMed

Youngentob, S.L., J.E. Schwob, S. Saha, G. Manglapus and B. Jubelt 2001 Functional consequences following infection of the olfactory system by intranasal infusion of the olfactory bulb line variant (OBLV) of mouse hepatitis strain JHM. Chem. Senses, 26: 953-963. PubMed

Zhuo, X., J.E. Schwob, P.J. Swiatek and X. Ding 2001 Mouse Cyp2G1 gene: Promoter structure and tissue-specific expression of a Cyp2G1-LacZ fusion gene in transgenic mice. Arch. Biochem. Biophys., 391: 127-136. PubMed

Shen, Y., S. Mani., S. Donovan, J.E. Schwob and K.F. Meiri 2002 GAP-43 is required for commissural axon guidance in the developing vertebrate telencephalon. J. Neurosci., 22: 239-247. PubMed

Leopold, D.A., T.A. Loehrl and J.E. Schwob 2002 Long-term follow-up of surgically treated phantosmia. Arch. Otolaryngol. Head Neck Surg., 128: 642-647. PubMed

Schwob, J.E. 2002 Neural regeneration and the peripheral olfactory system. Anat. Rec. (New Anat.), 269: 33-49. PubMed

Iwema, C.L., and J.E. Schwob 2003 Olfactory receptor expression as a function of neuronal maturity in the adult rodent olfactory system. J. Comp. Neurol., 459: 209-222.
PubMed

Jang, W., S.L. Youngentob, and J.E. Schwob 2003 Globose basal cells are required for reconstitution of olfactory epithelium after methyl bromide lesion. J. Comp. Neurol., 460: 123-140. PubMed

Chuah, M.I., J.E. Schwob, and A.I. Farbman 2003 Development of the olfactory system. In: R.L. Doty (Ed.) Handbook of Olfaction and Gustation, 2nd Edition, Marcel Dekker, New York, pp. 115-138.

Iwema, C.L., H. Fang, D. Kurtz, S. Youngentob, and J.E. Schwob 2004 Odorant receptor expression patterns are restored in lesioned-recovered rat olfactory epithelium. J. Neurosci., 24: 356-369. PubMed

Chen, X., H.Fang, and J.E. Schwob 2004 Multipotency of purified, transplanted globose basal cells in olfactory epithelium. J. Comp. Neurol., 469: 457-474. PubMed

Carr, V.McM., G. Ring, S.L. Youngentob, J.E. Schwob, and A.I. Farbman 2004 Altered epithelial density and expansion of bulbar projection of a discrete HSP70 immunoreactive subpopulation of rat olfactory receptor neurons in reconstituting olfactory epithelium after exposure to methyl bromide. J. Comp. Neurol., 469: 475-493. PubMed

Hamlin, J.A., H. Fang, and J.E. Schwob 2004 Differential expression of the mammalian homologue of Fasciclin II during olfactory development in vivoand in vitro. J. Comp. Neurol.,474: 438-452. PubMed

Manglapus, G.L., S.L. Youngentob, and J.E. Schwob 2004 Expression patterns of basic helix-loop-helix transcription factors define subsets of olfactory progenitor cells. J. Comp. Neurol., 479: 216-233. PubMed

Schwob, J.E. and W. Jang 2005 Stem cells of the adult olfactory epithelium. In: M. Rao (Ed.) Neural Development and Stem Cells, 2nd Ed. Humana, Totowa, NJ, pp. 219-233.

Schwob, J.E. 2005 Restoring olfaction: A view from the epithelium. Chem. Senses 30 (suppl):i131-i132. PubMed

Schwob, J.E., D.L. Kurtz and B.J. Goldstein 2005 Biology and testing of olfaction. In: T. Van De Water and H. Staecker (Eds.) Basic Science Review for Otolaryngology, Thieme, New York, in press.

Holbrook, E.H., D.A. Leopold and J.E. Schwob 2005 Abnormalities of axon growth in human olfactory mucosa. Laryngoscope, in press.

 

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