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John M. Coffin, Ph.D. |
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Professor of Molecular Biology and Microbiology
Genetics, Microbiology
john.coffin@tufts.edu
Our research interests revolve around obtaining a better understanding of the interaction of retroviruses with their host cells and organisms. We use simple retroviruses (avian and murine viruses) to elucidate the nature of the retrovirus-receptor interaction; the mechanism and specificity of integration of viral DNA into host DNA; control of viral gene expression; mechanism of retroviral genetic variation; and evolution of the host-virus relationship, as revealed by the ñfossilî record provided by endogenous proviruses found in the normal DNA of all vertebrates and many other species.
Visit the Coffin research web site |
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