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Beverly S. Rubin, Ph.D. |
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Associate Professor of Anatomy and Cellular Biology
Cell, Neuroscience
beverly.rubin@tufts.edu
Luteinizing hormone releasing hormone (LHRH), also known as gonadotropin releasing hormone (GnRH), is the primary hypothalamic signal that regulates gonadotropin synthesis and secretion from the pituitary. As a result this brain peptide is essential for reproductive fertility. In females, changing parameters of pulsatile LHRH release are important for the regulation of regular reproductive cyclicity and for the induction of the LH surge required for ovulation. Our lab is interested in further deciphering the exquisitely orchestrated and complex events involved in the regulation of LHRH gene expression, synthesis and secretion. Moreover, we are interested in determining how these essential events may be altered in aging or as a result of perturbationsexperienced during critical periods of development.
Visit the Rubin research web site |
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