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Carlos Sonnenschein, M.D. |
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Professor of Anatomy and Cellular Biology
Cell
carlos.sonnenschein@tufts.edu
Our laboratory works on the control of the initiation of the proliferation of estrogen-target cells. This basic biological question is explored under the fundamental premise that proliferation is the default state of all living cells. We have identified several plasma-borne and endogenously generated inhibitors of cell proliferation. In collaboration with Dr. Ana M. Soto, we have proposed the tissue organization field theory of carcinogenesis, which proposes that carcinogenesis is a tissue-based phenomenon. This notion challenges the one embodied in the somatic mutation theory of carcinogenesis, which posits that an accumulation of mutations in a single cell is responsible for the causation of a neoplasia.
Visit the Sonnenschein research web site |
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