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Douglas Vetter, Ph. D. |
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Assistant Professor of Neuroscience
Neuroscience
Cellular and Molecular Physiology
douglas.vetter@tufts.edu
We are interested in understanding the genetic basis for neurotransmission within the mammalian inner ear, as well as the development of the olivocochlear system. We are also interested in the genetic underpinning of hearing loss that occurs in response to acoustic over stimulation or exposure to ototoxic drugs. To investigate these broad interests, we use molecular biological techniques to generate transgenic mice lacking genes of interest. We then analyze these mice from anatomical, physiological, and biochemical perspectives by utilizing immunostaining, light and electron microscopy, auditory brainstem responses and distortion product otoacoustic emissions resulting from acoustic stimulation, and mass spectrometry and western blot analyses to investigate downstream effects of our transgenic manipulation on other cell signaling cascades.
Visit the Vetter research web site |
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