Selected Publications

Marko, M. G., Pang, H. J., Ren, Z., Azzi, A., Huber, B. T., Bunnell, S. C., and Meydani, S. N. 2009. Vitamin E reverses impaired linker for activation of T cells activation in T cells from aged C57BL/6 mice. J. Nutr. 139: 1192-1197.
[Abstract]

Nguyen, K., Sylvain, N. R., and Bunnell, S. C. T-cell costimulation via the integrin VLA-4 inhibits the actin-dependent centralization of signaling microclusters containing the adaptor SLP-76. Immunity 28: 810-821.
[Abstract]

Seminario, M. C. and Bunnell, S. C. 2008. Signal initiation in T-cell receptor microclusters. Immunol. Rev. 221, 90-106.
[Abstract]

Marko, M. G., Ahmed, T., Bunnell, S. C., Wu, D., Chung, H., Huber, B. T., and Meydani, S. N. 2007. Age-associated decline in effective immune synapse formation of CD4(+) T cells is reversed by vitamin E supplementation. J. Immunol. 178:1443-1449.
[Abstract]

Morley, S. C., Sung, J., Sun, G. P., Martelli, M. P., Bunnell S.C., and Bierer, B. E. 2007. Gelsolin overexpression alters actin dynamics and tyrosine phosphorylation of lipid raft-associated proteins in Jurkat T cells. Mol. Immunol. 44: 2469-2480.
[Abstract]

Bunnell S. C., Singer, A. L., Hong, D. I., Jacque, B. H., Jordan, M. S., Seminario, M. C., Barr, V. A., Koretzky, G. A., Samelson, L. E. 2006. Persistence of cooperatively stabilized signaling clusters drives T-cell activation. Mol. Cell. Biol. 26: 7155-7166.
[Abstract]

Barr, V. A., Balagopalan, L., Barda-Saad, M., Polishchuk, R., Boukari, H., Bunnell, S. C., Bernot, K. M., Toda, Y., Nossal, R., and Samelson, L. E. 2006. T-cell antigen receptor-induced signaling complexes: internalization via a cholesterol-dependent endocytic pathway. Traffic 7:1143-1162.
[Abstract]

Zipfel, P. A., Bunnell, S. C., Witherow, D. S., Gu, J. J., Chislock, E. M., Ring, C., and Pendergast, A. M. 2006. Role for the Abi/wave protein complex in T cell receptor-mediated proliferation and cytoskeletal remodeling. Curr Biol. 16: 35-46.
[Abstract]

Barda-Saad, M., Braiman, A., Titerence, R., Bunnell, S. C., Barr, V.A., and Samelson, L. E. 2005. Dynamic interactions linking the T cell receptor to the actin cytoskeleton. Nat. Immunol. 6: 80-89.
[Abstract]

Seminario, M. C., Precht, P., Bunnell, S. C., Warren, S. E., Morris, C. M., Taub, D., and Wange, R. L. 2004. PTEN permits acute increases in D3-phosphoinositide levels following TCR stimulation but inhibits distal signaling events by reducing the basal activity of Akt. Eur. J. Immunol. 34: 3165-3175.
[Abstract]

Singer, A. L., Bunnell, S. C., Obstfeld, A. E., Jordan, M. S., Wu., J. N., Myung, P. S., Samelson, L. E., and Koretzky, G. A. 2004. Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function. J. Biol. Chem. 279:15481-15490.
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Abstract]

Singer, A. L., Bunnell, S. C., Obstfeld, A. E., Jordan, M. S., Wu, J. N., Myung, P. S., Samelson, L. E., and Koretzky, G. A. 2003. Inhibition of T cell activation through interruption of adaptor protein associations. J. Surg. Res. 114: 271.
[Abstract]

Bunnell, S. C., Barr, A. V., Fuller, C. L., and Samelson, L. E. 2003. High-resolution multicolor imaging of dynamic signaling complexes in T cells stimulated by planar substrates. Science STKE Apr. 8 177: PL8.
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Abstract]