Selected Publications Hamer, D. H., Sempértegui, F., Estrella, B., Tucker, K. L., Rodríguez, A., Egas, J., Dallal, G. E., Selhub, J., Griffiths, J. K., and Meydani, S. N. 2008. Micronutrient deficiencies are associated with impaired immune response and higher burden of respiratory infections in elderly Ecuadorians. J. Nutr., Epub ahead of print. Meydani, S. N., and Wu, D. 2008.Nutrition and age-associated inflammation: implications for disease prevention. J Parenter Enteral Nutr. 32: 626-629. Wu, D., and Meydani, S. N. 2008. Age-associated changes in immune and inflammatory responses: impact of vitamin E intervention. J. Leukoc. Biol. 84: 900-914. Falsey AR, Dallal GE, Formica MA, Andolina GG, Hamer DH, Leka LL, Meydani SN. 2008. Long-Term Care Facilities: A Cornucopia of Viral Pathogens. J. Am. Geriatr. Soc. 56:1281-1285. Villamor, E., Mugusi, F., Urassa, W., Bosch, R. J., Saathoff, E., Matsumoto, K., Meydani, S. N., and Fawzi W. W. 2008. A trial of the effect of micronutrient supplementation on treatment outcome, T cell counts, morbidity, and mortality in adults with pulmonary tuberculosis. J. Infect. Dis. 197, 1499-1505. Ahmed, T., Hamer, D. H., and Meydani, S. N. 2008. Effects of repeated administration of intradermal skin test by Mantoux method on delayed-type hypersensitivity responses in healthy young and elderly subjects. Br. J. Nutr. 98, 1388-1390. Ren, Z., Guo, Z., Meydani, S. N., and Wu, D. 2008.
White button mushroom enhances maturation of bone marrow-derived dendritic cells and their antigen presenting function in mice. J Nutr. 138, 544-550. Meydani, S. N., and Wu, D. 2007. Age-associated inflammatory changes: role of nutritional intervention. Nutr Rev. 65, S213-216. Meydani, S. N., Barnett, J. B., Dallal, G. E., Fine, B. C., Jacques, P. F., Leka, L. S., and Hamer, D. H. 2007. Serum zinc and pneumonia in nursing home elderly. Am. J. Clin. Nutr. 86: 1167-1173. Wu, D., Ren, Z., Pae, M., Guo, W., Cui, X., Merrill, A. H., and Meydani, S. N. 2007. Aging up-regulates expression of inflammatory mediators in mouse adipose tissue. J. Immunol. 179: 4829-2839. Wu, D., Pae, M., Ren, Z., Guo, Z., Smith, D., and Meydani, S. N. 2007. Dietary supplementation with white button mushroom enhances natural killer cell activity in C57BL/6 mice. J. Nutr. 137: 1472-1477. Marko, M. G., Ahmed, T., Bunnell, S. C., Wu, D., Chung, H., Huber, B. T., and Meydani, S. N. 2007. Age-associated decline in effective immune synapse formation of CD4(+) T cells is reversed by vitamin E supplementation. J. Immunol. 178:1443-1449. Sempertegui, F., Estrella, B., Elmieh, N., Jordan, M., Ahmed, T., Rodriguez, A., Tucker, K. L., Hamer, D. H., Reeves, P. G., Meydani, S. N. 2006. Nutritional, immunological and health status of the elderly population living in poor neighbourhoods of Quito, Ecuador. Br J Nutr. 96: 845-853. Han, S. N., Adolfsson, O., Lee, C. K., Prolla, T. A., Ordovas, J., Meydani, S. N. 2006. Age and vitamin E-induced changes in gene expression profiles of T cells. J. Immunol. 177: 6052-6061. Gay, R. T., Belisle, S., Beck, M. A., and Meydani, S. N. 2006.
An aged host promotes the evolution of avirulent coxsackievirus into a virulent strain.
Proc Natl Acad Sci U S A. 103:13825-13830. Wu, D., Han, S. N., Meydani, M., and Meydani, S. N.
2006. Effect of concomitant consumption of fish oil and vitamin E on T cell mediated function in the elderly: a randomized double-blind trial. J Am Coll Nutr.
25: 300-306. Gismondi, P. M., Hamer, D. H., Leka, L. S., Dallal, G., Fiatarone Singh, M. A., and Meydani, S. N. 2005.
Strategies, time, and costs associated with the recruitment and enrollment of nursing home residents for a micronutrient supplementation clinical trial.
J. Gerontol. A. Biol. Sci. Med. Sci. 60:1469-1474. Wu, D., Liu, L., Meydani, M., and Meydani, S. N. 2005.
Vitamin E increases production of vasodilator
prostanoids in human aortic endothelial cells through opposing
effects on cyclooxygenase-2 and phospholipase A2. J. Nutri.
135: 1847-1853. Meydani, S. N., Han, S.N., and Wu, D. 2005.
Vitamin E and immune response in the aged: molecular
mechanisms and clinical implications. Immunol. Rev.
205: 269-284. Wu, D., Liu, L., Meydani, M., and Meydani,
S. N. 2004.
Effect of vitamin E on prostacyclin (PGI2) and
prostaglandin (PG) E2 production by human aorta endothelial
cells: mechanism of action. Ann. N.
Y. Acad. Sci. 1031: 425-427. Wu, D., Han, S. N., Meydani, M, and Meydani, S. N. 2004.
Effect of concomitant consumption of fish oil and
vitamin E on production of inflammatory cytokines in healthy
elderly humans. Ann. N.
Y. Acad. Sci. 1031: 422-424. Gay, R., Han, S. N., Marko, M., Belisle,
S., Bronson, R., and Meydani, S. N. 2004.
The effect of vitamin E on secondary bacterial infection
after influenza infection in young and old mice. Ann. N.
Y. Acad. Sci. 1031: 418-421. Ahmed, T., Marko,
M., Wu, D., Chung, H., Huber, B.,
and Meydani SN. 2004.
Vitamin E supplementation reverses the age-associated
decrease in effective immune synapse formation in CD4+
T cells. Ann. N. Y. Acad. Sci. 1031:
412-414. Meydani, S. N., Han, S. N., and Hamer, D.
H. 2004.
Vitamin E and respiratory infection in the elderly.
Ann. N. Y. Acad. Sci. 1031: 214-222. Han, S. N., Adolfsson, O., Lee, C. K., Prolla,
T. A., Ordovas, J., and Meydani, S. N. 2004.
Vitamin E and gene expression in immune cells. Ann.
N. Y. Acad. Sci. 1031: 96-101. Wu, D. and Meydani, S. N. 2004. Mechanism
of age-associated up-regulation in macrophage PGE(2) synthesis.
Brain Behav. Immun. 18: 487-494. Meydani, S. N., Leka, L. S., Fine, B. C.,
Dallal, G. E., Keusch, G. T., Singh, M. F., and Hamer, D.
H. 2004. Vitamin E and respiratory tract infections in elderly
nursing home residents: a randomized controlled trial. JAMA
292: 828-836. Adolfsson, O., Meydani, S. N., and Russell,
R. M. 2004. Yogurt and gut function. Am. J. Clin. Nutr.
80: 245-256. Han, S. N., leka, L. S., Lichtenstein,
A. H., Ausman, L. M., and Meydani, S. N. 2003. Effect of
therapeuitc lifestyle change diet on immune functions of
moderately hypercholesterolemic humans. J. Lipid Res. 44:
2304-2310. Santos, M. S., Lichtenstein, A. H., Leka,
L. S., Goldin, B., Schaefer, E. J., and Meydani, S. N. 2003.
Immunological effects of low-fat diets with and without
weight loss. J. Am. Coll. Nutr. 22: 174-182. Wu, D., Marko, M.
G., Claycombe, K. J., Paulson, K. E., and Meydani, S. N.
2003. Ceramide-induced and age-associated increase in macrophage
COX-2 expression is mediated through up-regulations of NF-kappaB
activity. J. Biol. Chem. 278: 10983-10992. Breitbart, E., Wnag,
X., Leka, L. S., Dallal, G. F., Meydani, S. N., and Stollar,
B. D. 2002. Altered memory B-cell homeostasis in human aging.
J. Gerontol. A. Biol. Sci. Med. Sci. 57: B304-311.
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