Selected Publications

Tapia-Páez, I., Tammimies, K., Massinen, S., Roy, A. L., and Kere, J. 2008. The complex of TFII-I, PARP1, and SFPQ proteins regulates the DYX1C1 gene implicated in neuronal migration and dyslexia. FASEB J. Epub ahead of print.
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Lazebnik, M. B., Tussie-Luna, M. I., and Roy, A. L. 2008. Determination and functional analysis of the consensus binding site for TFII-I family member BEN, implicated in Williams-Beuren syndrome. J. Biol. Chem. 283, 11078-11082.
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Roy, A. L. 2007. Signal-induced functions of the transcription factor TFII-I. Biochim. Biophys. Acta 1769: 613-621.
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Ashworth, T. and Roy, A. L. 2007. TFII-I controls B cell proliferation via regulating NF-κB. J. Immunol. J. Immunol. 178: 2631-2635.
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Roy, A. L. 2006. Transcription factor TFII-I conducts a cytoplasmic orchestra. ACS Chem. Biol. 1: 619-622.
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Hakre, S., Tussie-Luna, M. I., Ashworth, T., Novina, C. D., Settleman, J., Sharp, P. A.and Roy, A. L. 2006 Opposing functions of TFII-I spliced isoforms in growth factor induced gene expression. Mol. Cell 24: 301-308.
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Rajaiya, J,, Nixon, J. C., Ayers, N., Desgranges, Z. P., Roy, A. L., and Webb, C. F. 2006. Induction of immunoglobulin heavy-chain transcription through the transcription factor Bright requires TFII-I. Mol. Cell. Biol. 26: 4758-4768.
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Tussie-Luna, M. I., Rozo, L., and Roy, A. L. 2006. Pro-proliferative function of the long isoform of PML-RARα involved in acute promyelocytic leukemia. Oncogene 25: 3375-3386.
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Desgranges, Z. P. and Roy, A. L. 2006. TFII-I: connecting mitogenic signals to cell cycle regulation. Cell Cycle 5: 356-359.
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Desgranges, Z. P., Ahn, J., Lazebnik, M., Ashworth, T., Lee, C., Pestell, R. C., Rosenberg, N., Prives, C., and Roy, A. L. 2005. Inhibition of TFII-I-dependent cell cycle regulation by p53. Mol. Cell. Biol. 25: 10940-10952.
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Ku, M., Sokol. S. Y., Wu, J., Tussie-Luna, M. I., Roy, A. L., and Hata, A. 2005. Positive and negative regulation of the transforming growth factor β/activin target gene goosecoid by the TFII-I family of transcription factors. Mol. Cell. Biol. 25: 7144-7157.
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Hong, M., Lin, M., Huang, J. M., Baumeister, P., Hakre, S., Roy, A. L., and Lee, A. S. 2005. Transcriptional regulation of the Grp78 promoter by endoplasmic reticulum stress: Role of TFII-I and its tyrosine phosphorylation. J. Biol. Chem. 280: 16821-16828.
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Jiang, W., Sordella, R., Chen, G. C., Hakre, S., Roy, A. L., and Settleman, J. 2005. An FF domain-dependent protein interaction mediates a signaling pathway for growth factor-induced gene expression. Mol. Cell 17:23-25.
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Tantin, D., Tussie-Luna, M. I., Roy, A. L., and Sharp, P. A. 2004. Regulation of immunoglobulin promoter activity by TFII-I-class transcription factors. J. Biol. Chem. 279: 5460-5469.
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Sacristan, C., Tussie-Luna, I., Logan, S. M., and Roy, A. L. 2004. Mechanism of Btk-mediated recruitment and regulation of TFII-I. J. Biol. Chem. 279: 7147-7158.
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Wen, Y.-D., Cress, W. D., Roy, A. L., and Seto, E. 2003. Histone deacetylase 3 binds to and regulates the multifunctional transcription factor TFII-I. J. Biol. Chem. 278: 1841-1847.
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Cheriyath, V., Desgranges, Z. P., and Roy, A. L. 2002. c-Src dependent transcriptional activation of TFII-I. J. Biol. Chem. 277: 22798-22805.
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Tussie-Luna, M. I., Michel, B., Hakre, S., and Roy, A. L. 2002. The SUMO unbiquitin-protein isopeptide ligase family member Miz1/PIASxβ/Siz2 is a transcriptional co-factor for TFII-I family proteins. J. Biol. Chem. 277: 43185-43193.
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Tussie-Luna, M. I., Bayarshaihan, D., Seto, E., Ruddle, F. H., and Roy, A. L. 2002. Physical and functional interactions of histone deacetylase 3 with TFII-I family proteins and PIASxβ. Proc. Natl. Acad. Sci. USA 99: 12807-12812.
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Ji, H., Gupta, A., Okamoto, S., Blum, M. D., Tan, L., Golding, M. B., Lacy, E., Roy, A. L. and Terhorst, C. 2002. T cell-specific expression of the murine CD3 δ promoter. J. Biol. Chem. 277: 47898-47906.
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Cheriyath, V., and Roy, A. L. 2001. Structure-function analysis of TFII-I: roles of the N-terminal end, basic region and I-repeats. J. Biol. Chem. 276: 8377-8383.
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Parker, R., Phan, T., Baumeister, P., Roy, B., Cheriyath, V., Roy, A. L., and Lee, A. S. 2001. Identification of transcription factor TFII-I as the endoplasmic reticulum stress response element binding factor ERSF: its autoregulation by stress and interactions with ATF6. Mol. Cell. Biol. 21: 3220-3233.
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Tussie-Luna, M. I., Bayarshaihan, D., Ruddle, F. H., and Roy, A. L. 2001. Repression of TFII-I-dependent transcription by nuclear exclusion. Proc. Natl. Acad. Sci. USA 98: 7789-7794.
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Roy, A. L. 2001. Biology and biochemistry of the signal induced transcription factor TFII-I. Gene 274: 1-13
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Cheriyath, V., and Roy, A. L. 2000. Alternatively spliced isoforms of TFII-I: complex formation, nuclear translocation and differential gene regulation. J. Biol. Chem. 275, 26300-26308.
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Morikawa, N., Clarke, T. R., Novina, C. D., Watanabe, K., Haqq, C., Weiss, M., Roy, A. L., and Donahoe, P. K. 2000. Human mullerian-inhibiting substance promoter contains a functional TFII-I-binding initiator. Biol. Reprod. 63: 1075-1083.
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