Selected Publications

Wuerffel, R., Wang, L., Grigera, F., Manis, J., Selsing, E., Perlot, T., Alt, F. W., Cogne, M., Pinaud, E., and Kenter, A. L. 2007. S-S synapsis during class switch recombination is promoted by distantly located transcriptional wlements and activation-induced deaminase. Immunity 27: 711-722.
[Abstract]

Schrader, C. E., Guikema, J. E., Linehan, E. K., Selsing, E., and Stavnezer, J. 2007. Activation-induced cytidine deaminase-dependent DNA breaks in class switch recombination occur during G1 phase of the cell cycle and depend upon mismatch repair. J. Immunol. 179: 6064-6071.
[Abstract]

Han, J. H., Akira, S., Calame, K., Beutler, B., Selsing, E., and Imanishi-Kari, T. 2007. Class switch recombination and somatic hypermutation in early mouse B Cells are mediated by B Cell and toll-like receptors. Immunity 27: 64-75.
[Abstract]

Huang, F. T., Yu, K., Balter, B. B., Selsing, E., Oruc, Z., Khamlichi, A. A., Hsieh, C. L., and Lieber, M. R. 2007. Sequence dependence of chromosomal R-loops at the immunoglobulin heavy-chain Sμ class switch region. Mol. Cell. Biol. 27: 5921-5932.
[Abstract]

Selsing, E. 2006. Ig class switching: targeting the recombinational mechanism. Curr. Opin. Immunol. 18: 249-254.
[Abstract]

D'Avirro, N., Truong, D., Xu, B., and Selsing, E. 2005. Sequence transfers between variable regions in a mouse antibody transgene can occur by gene conversion. J. Immunol. 175: 8133-8137.
[Abstract]

Min, I. M., and Selsing, E., 2005. Antibody class switch recombination: roles for switch sequences and mismatch repair proteins. Adv. Immunol. 87: 297-328.
[Abstract]

Min, I. M., Rothlein, L. R., Schrader, C. E., Stavnezer, J., and Selsing, E. 2005. Shifts in targeting of class switch recombination sites in mice that lack μ switch region tandem repeats or Msh2. J. Exp. Med. 201: 1885-1890.
[Abstract]

Min, I. M., Schrader, C. E., Vardo, J., Luby, T. M., D'Avirro, N., Stavnezer, J., and Selsing, E. 2003. The sμ tandem repeat region is critical for Ig isotype switching in the absence of msh2. Immunity 19: 515-524.
[Abstract]

D'Avirro, N., Truong, D., Luong, M., Kanaar, R., and Selsing, E. 2002. Gene conversion-like sequence transfers between transgenic antibody V genes are independent of RAD54. J. Immunol. 169: 3069-3075.
[Abstract]

Tsai, H. F., D'Avirro, N., and Selsing, E. 2002. Gene conversion-like sequence transfers in a mouse antibody transgene: antigen selection allows sensitive detection of V region interactions based on homology. Int. Immunol. 14: 55-64.
[Abstract]

Luby, T. M., Sigurdardottir, D., Berger, E. D., and Selsing, E. 2001. Sequences associated with the mouse Sμ switch region are important for immunoglobulin heavy chain transgene expression in B cell development. Eur. J. Immunol. 31 :2866-2875.
[Abstract]

Luby, T. M., Schrader, C. E., Stavnezer, J., and Selsing, E. 2001. The μ switch region tandem repeats are important, but not required, for antibody class switch recombination. J. Exp. Med. 193: 159-168.
[Abstract]

Selsing, E., Xu, B., and Sigurdardottir, D. 1996. Gene conversion and homologous recombination in murine B cells. Semin. Immunol. 8:151-158.
[Abstract]

Sigurdardottir, D., Sohn, J., Kass, J., and Selsing, E. 1995. Regulatory regions 3' of the immunoglobulin heavy chain intronic enhancer differentially affect expression of a heavy chain transgene in resting and activated B cells. J. Immunol. 154: 2217-2225.
[Abstract]

Xu, B., and Selsing, E. 1994. Analysis of sequence transfers resembling gene conversion in a mouse antibody transgene. Science 265: 1590-1593.
[Abstract]

Sohn, J., Gerstein, R. M., Hsieh, C. L., Lemer, M., Selsing, E. 1993. Somatic hypermutation of an immunoglobulin μ heavy chain transgene. J. Exp. Med. 177: 493-504.
[Abstract]

Daitch, L. E., Moore, M. W., Persiani, D. M., Durdik, J. M., and Selsing, E. 1992. Transcription and recombination of the murine RS element. J. Immunol. 149: 832-840.
[Abstract]

Rath, S., Nisonoff, A., Selsing, E., and Durdik, J. M. 1991. B cell abnormalities induced by a μ Ig transgene extend to L chain isotype usage. J. Immunol. 146: 2841-2846.
[Abstract]

Gerstein, R. M., Frankel, W. N., Hsieh, C. L., Durdik, J. M., Rath, S., Coffin, J. M., Nisonoff, A., and Selsing, E. 1990. Isotype switching of an immunoglobulin heavy chain transgene occurs by DNA recombination between different chromosomes. Cell 63: 537-548.
[Abstract]

Borriero, L., Giorgetti, C., Smith, G., Landry, D., Selsing, E., Zhukovsky, E., and Press, J. L. 1990. Neonatal and adult primary B cells use the same germ-line VH and V κ genes in their (T,G)-A-L-specific repertoire. J. Immunol. 144: 583-592.
[Abstract]

Miller, J., Daitch, L., Rath, S., and Selsing, E. 1990. Tissue-specific expression of allogeneic class II MHC molecules induces neither tissue rejection nor clonal inactivation of alloreactive T cells. J. Immunol. 144: 334-341.
[Abstract]