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Stephane Duigou,
B.Sc., Genetics,
University Denis Diderot and Pierre et Marie Curie, Paris France,
The origin of replication of chromosome II of Vibrio cholerae (OricII) differs from that of chromosome I and from Oric of Escherichia coli. Replication at OricII requires two genes that flank OricII, rctB and rctA. rctB encodes an origin binding protein that is conserved across Vibrionaceae and rctA is an untranslated RNA. I am working to understand the function of these two genes and their role in chromosome II replication. |
