Selected Publications

O'Connor, R. M., Wanyiri, J. W., Cevallos, A. M., Priest, J. W., and Ward, H. D. 2007. Cryptosporidium parvum glycoprotein gp40 localizes to the sporozoite surface by association with gp15. Mol Biochem Parasitol. 156: 80-83.
[Abstract]

Bhat, N., Joe, A., PereiraPerrin, M., and Ward, H. D. 2007. Cryptosporidium p30, a galactose/N-acetylgalactosamine-specific lectin, mediates infection in vitro. J. Biol. Chem. 282: 34877-34887.
[Abstract]

Preidis GA, Wang HC, Lewis DE, Castellanos-Gonzalez A, Rogers KA, Graviss EA, Ward HD, White AC Jr. 2007. Seropositive human subjects produce interferon gamma after stimulation with recombinant Cryptosporidium hominis gp15. Am. J. Trop. Med. Hyg. 77:583-585.
[Abstract]

Wanyiri, J. W., O'Connor, R., Allison, G., Kim, K., Kane, A., Qiu, J., Plaut, A. G., and Ward, H. D. 2007. Proteolytic processing of the Cryptosporidium spp. glycoprotein gp40/15 by human furin and by a parasite-derived furin-like protease activity. Infect. Immun. 75: 184-192.
[Abstract]

Wanyiri, J. and Ward, H. D. 2006. Molecular basis of Cryptosporidium-host cell interactions: Recent advances and future perspectives. Future Microbiol. 1:201-208.

Stroup, S.E., Roy, S., McHele, J., Maro, V., Ntabaguzi, S., Siddique, A., Kang, G., Guerrant, R. L., Kirkpatrick, B. D., Fayer, R., Herbein, J., Ward, H., Haque, R., and Houpt, E.R. 2006. Real-time PCR detection and speciation of Cryptosporidium infection using Scorpion probes. J Med Microbiol. 55:1217-1222.
[Abstract]

Chhin, S., Harwell, J. I., Bell, J. D., Rozycki, G., Ellman, T., Barnett, J. M., Ward, H., Reinert, S. E., and Pugatch, D. 2006. Etiology of chronic diarrhea in antiretroviral-naive patients with HIV infection admitted to Norodom Sihanouk Hospital, Phnom Penh, Cambodia. Clin Infect Dis. 43:925-932.
[Abstract]

Godiwala, N. T., Vandewalle, A., Ward, H. D., and Leav, B. A. 2006. Quantification of in vitro and in vivo Cryptosporidium parvum infection by using real-time PCR. Appl. Environ. Microbiol. 72: 4484-4488.
[Abstract]

Muthusamy, D., Rao, S. S., Ramani, S., Monica, B., Banerjee, I., Abraham, O. C., Mathai, D. C., Primrose, B., Muliyil, J., Wanke, C. A., Ward, H. D., and Kang, G. 2006. Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India. J. Clin. Microbiol. 44: 632-634.
[Abstract]

Cohen, S., Dalle, F., Gallay, A., Di Palma, M., Bonnin, A., and Ward, H. D. 2006. Identification of Cpgp40/15 Type Ib as the predominant allele in isolates of Cryptosporidium spp. from a waterborne outbreak of gastroenteritis in South Burgundy, France. J. Clin. Microbiol. 44: 589-591.
[Abstract]

Rogers, K. A., Rogers, A. B., Leav, B. A., Sanchez, A., Vannier, E., Uematsu, S., Akira, S., Golenbock, D., and Ward, H. D. 2006. MyD88-dependent pathways mediate resistance to Cryptosporidium parvum infection in mice. Infect. Immun. 74: 549-556.
[Abstract]

Khan, W. A., Rogers, K. A., Karim, M. M., Ahmed S., Hibberd, P. L.,Calderwood, S. B., Ryan, E. T. and Ward, H. D. 2004. Cryptosporidiosis among Bangladeshi children with diarrhea: a prospective matched case control study of clinical features, epidemiology and systemic antibody responses. Am. J. Trop. Med. Hyg. 71: 412-419.
[Abstract]

Chen, X.M. O'Hara, S. P. Huang, B. Q., Nelson, J. B., Lin, J. J. C., Zhu, G., Ward, H. D. and LaRusso, N. F. 2004. Apical organelle discharge by Cryptosporidium parvum is temperature-, cytoskeleton- and intracellular calcium-eependent and required for host cell invasion. Infect. and Immun. 72: 6806-6816.
[Abstract]

O'Connor, R., Mackay, M. R., Ward, H. D. 2004. Molecular approaches for diagnosis, speciation and genotyping of Cryptosporidium. In: Molecular Microbiology, Diagnostic Principles and Practice. D. H. Persing, F. C. Tenover, J. Versalovic, Y. Tang, E. Unger, D.A. Relman and T.J. White, Eds., ASM Press, Washington, D.C. pp. 583-602.

O'Connor, R. M., Kim, K., Khan, F., and Ward, H. D. 2003. Expression of Cpgp40/15 in Toxoplasma gondii: a surrogate system for study of Cryptosporidium glycoprotein. Infect. Immun. 71: 6027-2034.
[Abstract]

Leav, B. A., Mackay, M., and Ward, H. D. 2003. Cryptosporidium species: new insights and old challenges. Clin. Infect. Dis. 37: 903-908.
[Abstract]

Chen, L., Williams, B. R., Yang, C.-Y., Cavallos, A. M., Bhat, N., Ward, H. D., and Sharon, J. 2003. Polyclonal Fab phage display libraries with a high percentage of diverse clones to Cryptosporidium parvum glycoproteins. Int. J. Parasitol. 33: 281-291.
[Abstract]

O’Connor, R. .M., Thorpe, C. M., Cevallos, A. .M., and Ward, H. D. 2002. Expression of the highly polymorphic Cryptosporidium parvum gp40/15 gene in genotype I and II isolates. Mol. Biochem. Parasitol. 119: 203-215.
[Abstract]

Leav, B. A., Mackay, M. R., Anyanwu, A., O'Connor, R. M., Cevallos, A. M., Kindra, G., Rollins, N., Nelson, R. G., Bennish, M. L., and Ward, H. D. 2002. Analysis of sequence diversity at the highly polymorphic Cpgp40/15 locus among Cryptosporidium isolates from HIV-infected children in South Africa. Infect. Immun. 70: 3881-3890.
[Abstract]

Sestak, K., Ward, L. A., Sheoran, A., Feng, X., Akiyoshi, D. E., Ward, H. D. and Tzipori, S. 2002. Variability among Cryptosporidium parvum genotype 1 and 2 immunodominant surface glycoproteins. Parasite Immunol. 24: 213-219.
[Abstract]

Widmer, G., Clancy, T., Ward, H. D., Miller, D., Batzer, G. M., Pearson, C. B., and Bukhari, Z. 2002. Structural and biochemical alterations in Giardia lamblia cysts exposed to ozone. J. Parasitol. 88: 1100-1106.
[Abstract]

Tzipori, S., and Ward, H. D. 2002. Cryptosporidiosis: biology, pathogenesis and disease, Microbes Infect. 4: 1047-1058.
[Abstract]

Bhat, N., and Ward, H. D. 2000. Lectin-mediated interaction of parasites with host cells. In: Lectins and Pathology, M. Caron and A. P. Seve, eds. Harwood Academic Publishers, Amsterdam, pp. 173-200.

Cevallos, A. M., Bhat, N., Verdon, R., Hamer, D., Stein, B., Tzipori, S., Pereira, M. E., Keusch, G. T. and Ward, H. D. 2000. Mediation of Cryptosporidium parvum infection in vitro by mucin-like glycoproteins defined by a neutralizing monoclonal antibody. Infect.Immun. 68: 5167-5175.
[Abstract]

Cevallos, A. M., Zhang, X., Waldor, M., Jaison, S., Tzipori, S., Zhou, X., Neutra, M., and Ward, H. D. 2000. Molecular cloning and expression of a gene encoding Cryptosporidium parvum glycoproteins gp40 and gp15. Infect. Immun. 68: 4008-4116.
[Abstract]