| Andrew
Camilli, Ph.D.
Professor, Department of Molecular Biology and Microbiology
and Howard Hughes Medical Institute. Analysis of host-pathogen interactions;
virulence factors of the human diarrheal pathogen Vibrio cholerae and
respiratory tract pathogen Streptococcus pneumoniae; regulation
of virulence gene expression during infection. |
Jenifer Coburn, Ph.D.
Associate Professor of Medicine, Departments of Medicine and of Molecular
Biology and Microbiology. Interactions of bacterial pathogens that
can establish
chronic infection with human cells. |
| John Coffin, Ph.D.
American Cancer Society Research Professor, Department of Molecular Biology
and Microbiology. Mechanisms of replication, expression, and integration
of retroviruses; mechanism of acquisition of retroviral oncogenes; molecular
biology of carcinogenesis; structure, genetics and evolution of endogenous
viruses; genetic variation and evolution of retroviruses; superantigens
of endogenous and exogenous retroviruses. |
| Edward Goldberg, Ph.D.
Professor, Department of Molecular Biology and Microbiology. Genetic design
and biological fabrication of parts for self-assembly of useful, functional
nanostructures. |
| Ekaterina Heldwein, Ph.D. Assistant Professor, Department
of Molecular Biology and Microbiology. Structural and mechanistic studies
of herpesvirus entry into host cells. |
| Linden Hu, M.D., Associate Professor of Medicine. Mechanisms of host adaptation by Borrelia burgdorferi; development of reservoir targeted vaccines for Lyme disease. |
| Ralph Isberg, Ph.D.
Professor, Department of Molecular Biology and Microbiology and Howard Hughes
Medical Institute Investigator. Analysis of entry and growth of intracellular
bacteria into host cells; molecular analysis of integrin receptor function;
growth and survival of bacterial pathogens in macrophages. |
Carol Kumamoto, Ph.D.
Professor, Department of Molecular Biology and Microbiology; Deputy Director,
Graduate Program in Molecular Microbiology. Invasive
growth of the fungal pathogen, Candida albicans. Mechanisms of
antifungal resistance in Candida albicans. |
| Michael H. Malamy, Ph.D.
Professor, Department of Molecular Biology and Microbiology. Transfer factors,
transposons and conjugal transposons responsible for DNA rearrangements
and dissemination in medically important bacteria; virulence factors in
the anaerobic pathogen Bacteroides fragilis and in vivo models
of infection. |
| Joan Mecsas, Ph.D.
Assistant Professor, Department of Molecular Biology and Microbiology. Study
of host-pathogen interactions using the bacterium Yersinia pseudotuberculosis.
|
| Claire Moore, Ph.D.
Professor, Department of Molecular Biology and Microbiology. Molecular mechanism
and regulation of mRNA 3' end formation in eukaryotic cells; genetic and
biochemical characterization of factors catalyzing polyadenylation and transcription
termination. |
| Alexander Poltorak, Ph.D., Assistant Professor of Pathology. The main focus of the lab is identification of novel regulators of the innate immune responses. These studies focus on genetic studies of the innate phenotypes in wild-derived strains of mice. In addition, role of innate immunity in development of autoimmunity is investigated using human CD14 transgenic mice. |
| Naomi Rosenberg, Ph.D.
Professor, Departments of Pathology and of Molecular Biology and Microbiology; Dean, Sackler School of Graduate Biomedical Sciences; Vice Dean for Research, School of Medicine.
Transformation of hematopoietic cells by abl oncogenes; mechanisms
of retrovirus transformation and differentiation arrest; molecular mechanisms
of immunoglobulin gene rearrangement; differentiation of lymphocytes (no longer taking new students for thesis research). |
| Brian Schaffhausen,
Ph.D. Professor, Departments of Biochemistry and of Molecular Biology
and Microbiology, Chair, Department of Biochemistry. Analysis of polyoma
virus transforming proteins and the normal pathways of signal transduction
with which they interact; role of protein phosphorylation in the regulation
of these processes. |
| Abraham L. Sonenshein,
Ph.D. Professor and Acting Chair, Department of Molecular Biology and Microbiology; Director,
Graduate Program in Molecular Microbiology. Regulation of bacterial differentiation
in Bacillus subtilis and Clostridium difficile; transcriptional
control of carbon and nitrogen metabolism genes in B. subtilis and Listeria monocytogenes; role of metabolic intermediates
in controlling gene expression and virulence; synthesis and secretion of bacterial toxins
and vaccine antigens (no longer taking new students for thesis research). |
 |
Professors Emeriti
|
| James T. Park Ph.D. Professor and Chair Emeritus, Department of Molecular Biology and Microbiology. |
| Moselio Schaecter, Ph.D.# Professor and Chair Emeritus, Department of Molecular Biology and Microbiology. Coauthor of "Small Things Considered" the microbiology blog. |
| Catherine L. Squires, Ph.D. Professor and Chair Emerita, Department of Molecular Biology and Microbiology.
Visiting Scientist, Department of Biological Sciences, Stanford University. Mechanisms of transcription antitermination. |
| Andrew
Wright, Ph.D. Professor, Department of Molecular Biology and Microbiology.
Regulation of DNA replication and chromosome segregation in Escherichia
coli; mechanisms of bacterial pathogenesis. |