Faculty and Research

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Andrew Camilli, Ph.D. Professor, Department of Molecular Biology and Microbiology and Howard Hughes Medical Institute. Analysis of host-pathogen interactions; virulence factors of the human diarrheal pathogen Vibrio cholerae and respiratory tract pathogen Streptococcus pneumoniae; regulation of virulence gene expression during infection.
John M. Coffin, Ph.D. American Cancer Society Research Professor, Department of Molecular Biology and Microbiology. Mechanisms of replication, expression, and integration of retroviruses; mechanism of acquisition of retroviral oncogenes; molecular biology of carcinogenesis; structure, genetics and evolution of endogenous viruses; genetic variation and evolution of retroviruses; superantigens of endogenous and exogenous retroviruses.
Edward B. Goldberg, Ph.D. Professor, Department of Molecular Biology and Microbiology. Genetic design and biological fabrication of parts for self-assembly of useful, functional nanostructures.
Ekaterina E. Heldwein, Ph.D. Assistant Professor, Department of Molecular Biology and Microbiology. Structural and mechanistic studies of herpesvirus entry into host cells.
Linden T. Hu, M. D., Associate Professor of Medicine. Mechanisms of host adaptation by Borrelia burgdorferi; development of reservoir targeted vaccines for Lyme disease. 
Ralph R. Isberg, Ph.D. Professor, Department of Molecular Biology and Microbiology and Howard Hughes Medical Institute Investigator. Analysis of entry and growth of intracellular bacteria into host cells; molecular analysis of integrin receptor function; growth and survival of bacterial pathogens in macrophages.
Carol A. Kumamoto, Ph.D. Professor, Department of Molecular Biology and Microbiology; Deputy Director, Graduate Program in Molecular Microbiology. Invasive growth of the fungal pathogen, Candida albicans. Mechanisms of
antifungal resistance in Candida albicans.
Michael H. Malamy, Ph.D. Professor, Department of Molecular Biology and Microbiology & Director, Graduate Program in Molecular Microbiology. Transfer factors, transposons and conjugal transposons responsible for DNA rearrangements and dissemination in medically important bacteria; virulence factors in the anaerobic pathogen Bacteroides fragilis and in vivo models of infection.
Joan Mecsas, Ph.D. Associate Professor, Department of Molecular Biology and Microbiology. Study of host-pathogen interactions using the bacterium Yersinia pseudotuberculosis.
Claire L. Moore, Ph.D. Professor, Department of Molecular Biology and Microbiology. Molecular mechanism and regulation of mRNA 3' end formation in eukaryotic cells; genetic and biochemical characterization of factors catalyzing polyadenylation and transcription termination.
Alexander Poltorak, Ph.D., Assistant Professor of Pathology. The main focus of the lab is identification of novel regulators of the innate immune responses. These studies focus on genetic studies of the innate phenotypes in wild-derived strains of mice. In addition, role of innate immunity in development of autoimmunity is investigated using human CD14 transgenic mice.
Naomi Rosenberg, Ph.D. Professor, Departments of Pathology and of Molecular Biology and Microbiology; Dean, Sackler School of Graduate Biomedical Sciences; Vice Dean for Research, School of Medicine. Transformation of hematopoietic cells by abl oncogenes; mechanisms of retrovirus transformation and differentiation arrest; molecular mechanisms of immunoglobulin gene rearrangement; differentiation of lymphocytes (no longer taking new students for thesis research).
Brian Schaffhausen, Ph.D. Professor and Chair, Department of Biochemistry. Analysis of polyoma virus transforming proteins and the normal pathways of signal transduction with which they interact; role of protein phosphorylation in the regulation of these processes.
Abraham L. Sonenshein, Ph.D. Professor and Acting Chair, Department of Molecular Biology and Microbiology. Regulation of bacterial differentiation in Bacillus subtilis and Clostridium difficile; transcriptional control of carbon and nitrogen metabolism genes in B. subtilis and Listeria monocytogenes; role of metabolic intermediates in controlling gene expression and virulence; synthesis and secretion of bacterial toxins and vaccine antigens (no longer taking new students for thesis research).
Honorine D. Ward, M.D. Professor of Medicine and Public Health. Analysis of host-parasite interactions of Cryptosporidium; Innate immunity to Cryptosporidium; Translational and clinical studies on cryptosporidiosis and other infectious diarrheal diseases in developing countries.

Professors Emeriti

James T. Park Ph.D. Professor and Chair Emeritus, Department of Molecular Biology and Microbiology.
Moselio Schaecter, Ph.D. Professor and Chair Emeritus, Department of Molecular Biology and Microbiology. Coauthor of "Small Things Considered" the microbiology blog.
Catherine L. Squires, Ph.D. Professor and Chair Emerita, Department of Molecular Biology and Microbiology. Visiting Scientist, Department of Biological Sciences, Stanford University. Mechanisms of transcription antitermination.
Andrew Wright, Ph.D. Professor Emeritus, Department of Molecular Biology and Microbiology. Regulation of DNA replication and chromosome segregation in Escherichia coli; mechanisms of bacterial pathogenesis.