Vibrio cholerae & Streptococcus pneumoniae
Camilli Laboratory


Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111

Lab (617) 636-6933
   

Anne Bishop, Ph.D.
Postdoctoral Fellow
Ph.D. University College, London
Post Doc at Imperial College, London (2001-2005)

Thesis Topic
Functional analysis of the Rac-Binding Protein POSH.

Current Research
I am interested in Vibrio cholerae host-pathogen interactions and cholera vaccine development.  I am working to further characterize an outer membrane vesicle-based cholera vaccine in a mother-to-neonate mouse protection model.  In particular, identifying major protective antigens and investigating protection from host-passage hyper-infectious V. cholerae.  I am also investigating innate immune responses to V. cholerae infection in the suckling mouse model.

Publications

  1. S Schild, Nelson E, Bishop A and Camilli A.  “Characterization of Vibrio cholerae Outer Membrane Vesicles as a candidate Vaccine for Cholera” – Infection and Immunity (2009) 77: 472-84 WEB LINK

  2. T Song, Mika F, Lindmark B, Liu Z, Schild X, Bishop A, Zhu J, Camilli A, Johansson J, Vogel J, Wai SN. “A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles” – Molecular Microbiology (2008) 70:100-11 WEB LINK

  3. EJ Nelson, Chowdhury A, Harris JB, Begum YA, Chowdhury F, Khan AI, LaRocque RC, Bishop AL, Ryan ET, Camilli A, Qadri F, and Calderwood SB. “Complexity of rice-water stool from patients with Vibrio cholerae plays a role in the transmission of infectious diarrhea”. – PNAS (2007) 104:19091-6 WEB LINK

  4. S Schild, Bishop A and Camilli A. “Ins and Outs of Vibrio cholerae” – ASM Microbe Magazine (2008) 3:131-136, features article

  5. A Bishop, House D, Perkins T, Baker S, Kingsley R and Dougan G. “Interaction of Salmonella enterica serovar Typhi with cultured epithelial cells: roles of surface structures in adhesion and invasion” – Microbiology (2008) 154: 1914-26
    WEB LINK

  6. A Bishop, Wiles S, Dougan G and Frankel G. “Cell attachment properties and infectivity of host-adapted and environmentally-adapted Citrobacter rodentium” – Microbes and Infection (2007) 9:1316-24
    WEB LINK

  7. A Bishop, Baker S, Jenks S, Fookes M, O’Gaora P, Pickard D, Anjum M, Farrar J, Hien T, Ivens A and Dougan G. “Analysis of the hypervariable region of the Salmonella enterica genome associated with tRNAleuX ” – Journal of Bacteriology (2005) 187: 2469-2482 WEB LINK

  8. A Bishop, Dougan G and Baker S. “The Salmonella genome: a global view”, chapter within “Salmonella Infections: Clinical, Immunological and Molecular Aspects”, Cambridge University Press, editors P Mastroeni and D Maskell (2005) - In press book chapter

  9. A Bishop and Hall A. “Rho GTPases and their effector proteins” –
    Biochemical Journal (2000) 348:241-255, Review