Vibrio cholerae & Streptococcus pneumoniae


Principal Investigator
Andrew Camilli
Professor

Program Affiliations
Molecular Microbiology

Contact Information
Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111

Office (617) 636-2144
Lab (617) 636-6933
Fax (617) 636-2175
Email  
Andrew.Camilli@tufts.edu
  1. Angelichio, M. A., D. S. Merrell, and A. Camilli. 2004.  “Spatiotemporal Analysis of Acid Adaptation-Mediated Vibrio cholerae Hyperinfectivity”. Infect. Immun. 72:2405-7. 
  2. Butler, S. M. and A. Camilli. 2004. “Both chemotaxis and net motility greatly influence the infectivity of Vibrio cholerae”. Proc. Natl. Acad. Sci. (USA) 101:5018-23.
  3. Osorio, C. G., H. Martinez-Wilson and A. Camilli . 2004. “The ompU paralogue vca1008 is required for virulence of Vibrio cholerae”. J. Bacteriol. 186:5167-71.
  4. Tischler, A. D. and A. Camilli. 2004. “Cyclic Diguanylate (c-di-GMP) Regulates Vibrio cholerae Biofilm Formation”. Mol. Microbiol. 53:857-69.
  5. Osorio, C. G. , J. A. Crawford, J. Michalsky, H. Martinez-Wilson, J. B. Kaper and A. Camilli.  2005.  “Second-generation recombination-based in vivo expression technology for large-scale screening for Vibrio cholerae genes induced during infection of the mouse small intestine”.  Infect. Immun. 73:972-80.
  6. Tischler, A. D. and A. Camilli. 2005. “Cyclic Diguanylate Regulates Vibrio cholerae Virulence Gene Expression”. Infect. Immun. 73(9):5873-82.
  7. Tamayo, R., A. D. Tischler, and A. Camilli. 2005. “The EAL domain protein VieA is a cyclic diguanylate phosphodiesterase”. J. Biol. Chem. 280(39):33324-30.
  8. Iyer, R., N. S. Baliga and A. Camilli. 2005. “Catabolite control protein A (CcpA) contributes to virulence and regulation of sugar metabolism in Streptococcus pneumoniae”. J. Bacteriol. 187(24):8340-9.
  9. Butler, S. M., E. J. Nelson, N. Chowdhury, S. M. Faruque, S. B. Calderwood and A. Camilli. 2006. “Cholera stool bacteria repress chemotaxis to increase infectivity”. Mol. Microbiol. 60:417-26.
  10. LeMieux, J., D.L. Hava, A. Basset and A. Camilli. 2006. “RrgA and RrgB are components of a multisubunit pilus encoded by the Streptococcus pneumoniae rlrA pathogenicity islet”. Infect Immun. 74:2453-6.
  11. Pratt J. T., R. Tamayo, A. D. Tischler and A. Camilli. 2007. “PilZ domain proteins bind cyclic diguanylate and regulate diverse processes in Vibrio cholerae”. J Biol Chem. 27:12860-70.
  12. Iyer, R., and A. Camilli.  2007. “Sucrose metabolism contributes to in vivo fitness of Streptococcus pneumoniae”.  Mol. Microbiol. 66:1-13.
  13. Nelson, E. J., Chowdhury, A., Harris, J. B., Chowdhury, F., Khan, A. I., Begum, Y. A., LaRocque, R. C., Bishop, A., Ryan, E. T., A. Camilli, E. T., Qadri, F., S. B. Calderwood. 2007. “Complexity of rice-water stool from patients with Vibrio cholerae plays a role in the transmission of infectious diarrhea”. Proc. Natl. Acad. Sci. (USA), 104(48):19091-6.
  14. Schild, S., Tamayo, R., Nelson, E. J., Qadri, F., Calderwood, S. B. and A. Camilli. 2007. “Genes induced late in infection increase fitness of Vibrio cholerae after release into the environment”. Cell Host Microbe, 2(4):264-77.
  15. Tamayo, R., S. Schild, J. T. Pratt and A. Camilli. 2008. “Role of Cyclic Di-GMP During El Tor biotype Vibrio cholerae Infection: Characterization of the In Vivo Induced Cyclic Di-GMP Phosphodiesterase CdpA”. Infect. Immun., 76(4):1617-27.
  16. LeMieux, J., S. Woody and A. Camilli. 2008. “Roles of the sortases of Streptococcus pneumoniae in assembly of the RlrA pilus”. J Bacteriol 190:6002-13.
  17. Martinez-Wilson, H. F., R. Tamayo, A. D. Tischler, D. W. Lazinski and A. Camilli. 2008. “The Vibrio cholerae hybrid sensor kinase VieS contributes to motility and biofilm regulation by altering cyclic diguanylate level”. J. Bacteriol. 190:6439-47.
  18. Schild, S., E. J. Nelson and A. Camilli. 2008. “Immunization with Vibrio cholerae outer membrane vesicles induces protective immunity in mice”. Infect Immun. 76:4554-63.
  19. Munoz-Elias, E. J., J. Marcano and A. Camilli. 2008. “Isolation of Streptococcus pneumoniae biofilm mutants and their characterization during nasopharyngeal colonization”. Infect Immun. 76:5049-61.
  20. Nelson, E. J., A. Chowdhury, J. Flynn, S. Schild, L. Bourassa, Y. Shao, R. C. LaRocque, S. B. Calderwood, E. T. Qadri and A. Camilli. 2008. “Transmission of Vibrio cholerae is antagonized by lytic phage and entry into the viable but nonculturable state”. PLoS Pathogens, (in press).