Principal Investigator
Carol Kumamoto
Professor
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Program Affiliations
Genetics
Molecular Microbiology
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Contact Information
Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111
Office (617) 636-0404
Lab (617) 636-6803
Fax (617) 636-0337
Send Email
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Selected Publications
Kumamoto, C.A. and Vinces, M.D. 2005.
Contributions of hyphae and hypha-coregulated genes to
Candida albicans virulence. (In press)
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Kumamoto, C.A. and Vinces, M.D. 2005.
Alternative Candida albicans Lifestyles: Growth
on Surfaces. Ann. Rev. Microbiol. 59,113–33
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Kumamoto, C.A. 2005. A contact-activated
kinase signals Candida albicans invasive growth
and biofilm formation.
Proc. Natl. Acad. Sci (USA)102, 5576-81.
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Chen, X., B.B. Magee, D. Dawson, P.T.
Magee and C.A. Kumamoto. 2004. Chromosome
1 trisomy compromises the virulence of Candida albicans.
Mol. Microbiol. 51, 551-565.
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Schierle, C.F., M. Berkmen, D. Huber,
C. Kumamoto, D. Boyd and J. Beckwith. 2003. The
DsbA signal sequence directs efficient, cotranslational
export of passenger proteins to the Escherichia
coli periplasm via the signal recognition particle
pathway. J. Bacteriol. 185, 5706-5713.
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Kumamoto, C.A. 2002.
Fungal biofilms. Curr. Opin. Microbiol. 5,
608-11.
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Giusani, A.D., M. Vinces and C.A.
Kumamoto. 2002. Invasive filamentous growth
of Candida albicans is promoted by Czf1p-dependent
relief of Efg1p-mediated repression. Genetics 160,
1749-1753. PubMed
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Riggle, P.J. and C.A. Kumamoto.
2000. Role of a Candida albicans P1-type ATPase
in resistance to copper and silver ion toxicity. J. Bacteriol. 182,
4899-4905. PubMed
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Woodbury, R.L., T.B. Topping, D.L.
Diamond, D. Suciu, C.A. Kumamoto, S.J.S.
Hardy and L.L. Randall. 2000. Complexes between protein
export chaperone SecB and SecA: Evidence for separate
sites on SecA providing binding energy and regulatory
interactions. J. Biol. Chem. 275, 24191-24198.
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Andrutis, K.A., P.J. Riggle, C.A.
Kumamoto and S.R. Tzipori. 2000. Intestinal
lesions associated with disseminated candidiasis in
an experimental animal model. J. Clin. Microbiol. 38,
2317-2323. PubMed
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Brown, D.H., Jr., A.D. Giusani, X.
Chen and C.A. Kumamoto. 1999. Filamentous
growth of Candida albicans in response to physical
environmental cues, and its regulation by the unique
CZF1 gene. Mol. Microbiol. 34, 651-662. PubMed
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Muren, E.M., D. Suciu, T.B. Topping,
C.A. Kumamoto and L.L. Randall. 1999. Mutational
alteration in the homotetrameric chaperone SecB that
implicate the structure as dimer of dimers. J. Biol.
Chem. 274, 19397-19402.
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Riggle, P.J., K.A. Andrutis, X. Chen,
S.R. Tzipori and C.A. Kumamoto. 1999.
Invasive lesions containing filamentous forms produced
by a Candida albicans mutant that is defective
in filamentous growth in culture. Infect. Immun. 67,
3649-3652. PubMed
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Cook, H.A. and C.A. Kumamoto.
1999. Overproduction of SecA suppresses the export defect
caused by a mutation in the gene encoding the Escherichia
coli export chaperone SecB. J. Bacteriol. 181,
3010-3017. PubMed
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| Fekkes, P, J.G. de Wit, J.P.W. van
der Wolk, H.H. Kimsey, C.A. Kumamoto,
and A.J.M. Driessen. 1998. Preprotein transfer to the Escherichia
coli translocase requires the cooperative binding
of SecB and the signal sequence to SecA. Mol. Microbiol. 29,
1179-1190. PubMed |
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