Lazinski Laboratory [Program Faculty | Department Faculty]

Hepatitis Viruses

Principal Investigator
David Lazinski
Assistant Professor
 
Program Affiliations
Molecular Microbiology
 
Contact Information
Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111
Office (617) 636-3671
Lab (617) 636-0474
Fax (617) 636-0337
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Selected Publications

Sato S., Cornillez-Ty C.T. and D.W. Lazinski. 2004. By inhibiting replication, the large hepatitis delta antigen can regulate amber/W editing and its own expression. J Virol. Aug; 78(15):8120-34.
Das A., J. Garcia Mena J, N. Jana, D. Lazinski, G. Michaud, S. Sengupta and Z. Zhang. 2003. Genetic and biochemical strategies to elucidate the architecture and targets of a processive transcription antiterminator from bacteriophage lambda. Methods Enzymol. 371:438-59.
Wong S.K., S. Sato and D.W. Lazinski. 2003. Elevated activity of the large form of ADAR1 in vivo: very efficient RNA editing occurs in the cytoplasm. RNA 9:586-98.
Cornillez-Ty C, and Lazinski DW. 2003. Determination of the multimerization state of the hepatitis delta antigens in vivo. J. Virol. Oct; 77(19):10314-26.
Wong SK, Lazinski DW. 2002. Replicating hepatitis delta virus RNA is edited in the nucleus by the small form of ADAR1. Proc Natl Acad Sci U S A. Nov 12; 99(23):15118-23.
O'Malley B, Lazinski D. 2002. A hepatitis B surface antigen mutant that lacks the antigenic loop region can self-assemble and interact with the large hepatitis delta antigen. J Virol. Oct; 76(19):10060-3.
Sato S, Wong SK, Lazinski DW. 2001. Hepatitis delta virus minimal substrates competent for editing by ADAR1 and ADAR2. J Virol. Sep; 75(18):8547-55.
Wong SK, Sato S, Lazinski DW. 2001. Substrate recognition by ADAR1 and ADAR2. RNA. Jun; 7(6):846-58. PubMed
Reid CE, Lazinski DW. 2000. A host-specific function is required for ligation of a wide variety of ribozyme-processed RNAs. Proc Natl Acad Sci U S A. Jan 4; 97(1):424-9. PubMed
 
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