Principal Investigator
Michael Malamy
Professor
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Program Affiliations
Genetics
Molecular Microbiology
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Contact Information
Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111
Office (617) 636-6756
Lab (617) 636-6757
Fax (617) 636-0337
Send Email |
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Selected Publications
Brigham, C and M.H. Malamy. 2004.
Characterization of the RokA and HexA broad substrate
specificity hexokinases from Bacteroides fragilis and
their role in hexose and N-acetylglucosamine utilization.
J Bacteriol (in press).
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Baughn A.D. and M.H. Malamy. 2004.
The strict anaerobe Bacteroides fragilis grows
in and benefits from nanomolar concentrations of oxygen.
Nature. 427:441-4
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Baughn A.D. and M.H. Malamy. 2003.
The essential role of fumarate reductase in haem-dependent
growth stimulation of Bacteroides fragilis.
Microbiology. 149(Pt 6):1551-8
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Shi D, Gallegos R, DePonte J 3rd,
Morizono H, Yu X, Allewell NM, Malamy M, Tuchman M.
2002. Crystal structure of a transcarbamylase-like
protein from the anaerobic bacterium Bacteroides
fragilis at 2.0 A resolution. J Mol Biol. 19;320(4):899-908.
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Caldovic L, Morizono H, Yu X, Thompson
M, Shi D, Gallegos R, Allewell NM, Malamy MH, Tuchman
M. 2002. Identification, cloning and expression of
the mouse N-acetylglutamate synthase gene. Biochem
J. 15;364(Pt 3):825-31.
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Baughn AD, Malamy MH. 2002. From
the Cover: A mitochondrial-like aconitase in the bacterium Bacteroides
fragilis: Implications for the evolution of the
mitochondrial Krebs cycle. Proc Natl Acad Sci U S A.
2;99(7):4662-7.
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Chen T, Dong H, Tang YP, Dallas
MM, Malamy MH, Duncan MJ. 2000. Identification and
cloning of genes from Porphyromonas gingivalis after
mutagenesis with a modified Tn4400 transposon from Bacteroides
fragilis. Infect Immun. 68(1):420-3.
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Tang YP, Malamy MH. 2000. Isolation
of Bacteroides fragilis mutants with in vivo
growth defects by using Tn4400', a modified Tn4400
transposition system, and a new screening method. Infect
Immun.68(1):415-9.
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Tang YP, M.M. Dallas and M.H. Malamy.
1999. Characterization of the BatI (Bacteroides
Aerotoloerance) Operon in Bacteroides fragilis:
Isolation of a B. fragilis mutant with reduced
aerotolerance and impaired growth in in vivo model
systems. Molecular Microbiology 32:139-149. PubMed
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| Rajagopal, B.S., J. DePonte III,
M. Tuchman and M.H. Malamy. (1998) Use of feedback
resistant N-acetylglutamate synthetase for enhanced
biosynthesis of arginine by engineered E. coli K12
strains. Applied Environ. Micro. 64:1805-1811. PubMed |
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