Principal Investigator
Joan Mecsas
Assistant Professor
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Program Affiliations
Molecular Microbiology
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Contact Information
Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111
Office (617) 636-2742
Lab (617) 636-2743
Fax (617) 636-0337
Send Email |
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Selected Publications
Balada, J. M., and Mecsas, J. 2006
Yersinia has a tropism for B and T cell zones of lymph
node that is independent of the Type III secretion
system. PLoS Pathogen. Epub ahead of print.
[Abstract]
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Logsdon, L. K., and Mecsas, J. 2006.
A non-invasic quantitative assay to measure murine
intestinal inflammation using the neutrophil marker
lactoferrin.J. Immunol. Meth. 313:183-190.
[Abstract]
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Barnes, P. D., Bergman, M. A.,
Mecsas, J., and Isberg, R. R. 2006. Yersinia pseudotuberculosis
disseminates directly from a replicating bacterial
pool in the intestine. J. Exp. Med. Epub ahead of
print.
[Abstract]
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Logsdon, L. K. and Mecsas, J.
2006. The proinflammatory response induced by wild-type
Yersinia pseudotuberculosis infection inhibits survival
of yop mutants in the gastrointestinal tract and
Peyer's patches. Infect. Immun. 74:1516-1527.
[Abstract]
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Mecsas, J., Franklin, G., Kuziel,
W. A., Brubaker, R. R., Falkow, S., and Mosier, D.E.,
2004. Evolutionary Genetics: CCR5 mutation and plague
protection. Nature 427: 606.
[Abstract]
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Logsdon, L. K. and Mecsas, J. 2003.
Requirement of the Yersinia pseudotuberculosis type
III secreted effectors YopH and YopE in colonization
and persistence in intestinal and lymph tissues. Infect
and Immun. 71: 4595-4907 .
[Abstract]
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Mecsas, J. 2002. Use of signature-tagged
mutagenesis in pathogenesis studies. Current Opin.
Microbiol. 5: 33-37.
[Abstract]
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Mecsas, J., Bilis, I. and Falkow,
S. 2001. Identification of attenuated Yersinia
pseudotuberculosis strains and characterization of an orogastric infection
in BALB/c mice on day 5 post-infection by signature-tagged
mutagenesis. Infect. Immun. 69: 2779-2787.
[Abstract]
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Yao, T., Mecsas, J., Healy, J.,
Falkow, S. and Chien Y.-N. 1999. Supression of T and
B cell lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, YopH. J. Exp. Med . 190:1343-1350
[Abstract]
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Raupach, B., Mecsas, J., Heczko,
U., Falkow, S., and Finlay, B. B. 1999. Bacterial epithelial
cell cross talk. Curr. Top. Microbiol. Immunol. 236:
137-161.
[Abstract]
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Monack, D. M., Mecsas, J., Bouley,
D.and Falkow, S. 1998. Yersinia-induced apoptosis in
vivo aids in the establishment of a systemic infection
of mice. J. Exp. Med. 188:11, 2127-2137
[Abstract]
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Mecsas, J., Raupach, B., and Falkow,
S. 1998. The Yersinia Yops inhibit invasion of Listeria,
Shigella and Edwardsiella, but not Salmonella into
epithelial cells. Mol. Micro. 28: 1269–1282.
[Abstract]
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