Messenger RNA Processing

James Gordon
Postdoctoral Associate
Ph.D., The University of Manchester, Biomolecular Sciences
B.Sc. (Hons), UMIST, Biochemistry with Biotechnology

Thesis Topic
Interaction studies of RNase MRP subunits

Current Research
I am studying the mRNA 3' end processing machinery from a structural perspective.
The current focus of my work is in the use of x-ray crystallography and single
particle electron microscopy to study CF1 and its component subunits.

Publications

1. Gordon JM, Aspinall TV, Bennett HJ, Karahalios P, Bukowski JP, Walker
   SC, Engelke DR, Avis JM. 2007. Interactions between subunits of Saccharomyces
   cerevisiae RNase MRP support a conserved eukaryotic RNase P/MRP
   architecture. Nucleic Acids Res. 35(19):6439-50.
2. Walker SC, Aspinall TV, Gordon JM, Avis JM. 2005. Probing the structure of
   Saccharomyces cerevisiae RNase MRP. Biochem Soc Trans. 33(Pt 3):479-81.