Principal Investigator
Naomi Rosenberg
Professor
|
Program Affiliations
Genetics
Immunology
Molecular Microbiology
|
Contact Information
Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111
Office (617) 636-2143
Lab (617) 636-0307
Fax (617) 636-0337
Send Email |
|
Selected Publications
Desgranges, Z. P., Ahn, J., Lazebnik,
M., Ashworth, T., Lee, C., Pestell, R. C., Rosenberg,
N., Prives, C., and Roy, A. L. 2005. Inhibition of
TFII-I-dependent cell cycle regulation by p53. Mol.
Cell. Biol. 25, 10940-10952.
[Abstract]
|
Marchlik, E., Kalman, R., and Rosenberg,
N. 2005. Decreased virus population diversity in p53
null mice infected with weakly oncogenic Abelson virus.
J. Virol. 79: 11618-11626.
[Abstract]
|
Baughn, L. B. and Rosenberg, N.
2005. Disruption of the Shc/Grb2 complex during Abelson
virus transformation affects proliferation, but not
apoptosis. J. Virol. 79:2325-2334.
[Abstract]
|
Sachs, Z., Sharpless, N. E., DePinho,
R. A., and Rosenberg, N. 2004. p16Ink4a interferes
with Abelson virus transformation by enhancing apoptosis.
J. Virol. 78: 3304-3311.
[Abstract]
|
Kharas, M. G., Deane, J. A., Wong,
S., O'Bosky, K. R., Rosenberg, N., Witte, O. N., and
Fruman, D. A. 2004. Phosphoinositide 3-kinase is essential
for Abl oncogene mediated transformation of B lineage
cells. Blood 103: 4268-4275.
[Abstract]
|
Gong, L., Unnikrishnan, I., Raghavan,
A., Parmar, K. and Rosenberg, N. 2004. Active Akt and
functional p53 modulate apoptosis in Abelson virus-transformed
pre-B cells. J. Virol. 78: 1636-1644.
[Abstract]
|
Unnikrishnan, I. and Rosenberg,
N. 2003. The absence of p53 complements defects in
Abelson murine leukemia virus signaling. J. Virol.
77: 6208-2003.
[Abstract]
|
Warren, D. W., Griffin, D., Mainville,
C. A., and Rosenberg, N. 2003. The carboxyl terminus
of v-Abl mediates protein stability in pre-B lymphocytes.
J. Virol. 77: 4617-4625.
[Abstract]
|
Rosenberg, N. 2001. New transformation
tricks from a barnyard retrovirus - Implications for
human lung cancer. Proc. Natl. Acad. Sci. U. S. A.
98: 4285-4287.
[Abstract]
|
Mainville, C., Parmar, K., Unnikrishnan,
I. Raffel G. D., Gong, L., and Rosenberg, N. 2001.
Alteration of the FLVRES motif in the v-Abl SH2 domain
confers a temperature sensitive transformation phenotype.
J. Virol. 75:1816-1823.
[Abstract]
|
Warren, D., Heilpern, A. J., Berg,
K., and Rosenberg, N. 2000. The carboxyl terminus of
v-Abl protein can augment SH2 domain function. J. Virol.
74: 4495-4504.
[Abstract]
|
Mostecki, J., Halgren, A. Sachs,
Z., Radfar, A., Ravitz, J., Thome, K. C., and Rosenberg,
N. 2000. Loss of heterozygosity at the Ink4a/Arf locus
facilitates Abelson virus transformation of pre-B cells.
J. Virol. 74: 9479-9487.
[Abstract]
|
Jenab-Wolcott, J., Rodriguez-Correa,
D., Reitmair, A., Mak, T., and Rosenberg, N. 2000.
The absence of Msh2 alters Abelson virus pre-B cell
transformation by influencing p53 mutation. Mol. Cell.
Biol. 20: 8373-8381.
[Abstract]
|
Unnikrishnan, I., Radfar, A., Jenab-Wolcott,
J., and Rosenberg, N. 1999. p53 mediates apoptotic
crisis in primary Ab-MLV-transformed pre-B cells. Mol.
Cell. Biol. 19: 4825-4831.
[Abstract]
|
Coffin, J. M. and Rosenberg, N.
1999. Retroviruses. Closing the joint. Nature 413:
415-416.
[Abstract]
|
Radfar, A., Unnikrishnan, I., Lee,
H.-W., DePinho, R., and Rosenberg, N.1998. p19ARF induces
p53-dependent apoptosis during Abelson virus-mediated
pre-B cell transformation. Proc. Natl. Acad. Sci. U.S.A.
95: 13194-13199.
[Abstract]
|
Thome, K., Radfar, A., and Rosenberg,
N. 1997. Mutations in Tp53 contribute to the malignant
phenotype of Abelson virus-transformed cells. J. Virol.
71: 8149-8156.
[Abstract]
|
Liu, D. J. Jenab, and N. Rosenberg.
1997. kappa and lambda rearrangement occur simultaneously
in transformed pre-B cells. J. Immunol. 159: 6061-6069.
[Abstract]
|
Afar, D. E. H., Han, L., McLaughlin,
J., Wong, S., Dhaka, A., Parmar, K., Rosenberg, N.,
Witte, O. N., and Colicelli, J. 1997. Regulation of
the oncogenic activity of BCR-ABL by a tightly bound
substrate protein RIN1. Immunity 6: 773-782.
[Abstract]
|
Bailey, S. N. and N. Rosenberg.
1997. Assessing the pathogenic potential of the V(D)J
recombinase by interlocus immunoglobulin light chain
gene rearrangement. Mol. Cell. Bio. 17: 887-894.
[Abstract]
|
Rosenberg, N. and Jolicoeur, P.
1997. Retrovirus Pathogenesis, in Retroviruses, J.
Coffin, S. Hughes, and H. Varmus, eds., Cold Spring
Harbor Laboratory Press, Cold Spring Harbor, NY, pp
475-586.
[Abstract] |
|
|