Principal Investigator
Brian Schaffhausen
Professor and Chair of Biochemistry
Program Affiliations
Biochemistry
Immunology
Molecular Microbiology
Contact Information
Department of Microbiology
Tufts University
136 Harrison Avenue
Boston, MA 02111
| Office |
(617) 636-6876 |
| Lab |
(617) 636-6868 |
| Fax |
(617) 636-2409 |
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We are interested in regulation of mammalian cell growth and cellular signal transduction. The lab is particularly interested in protein phosphorylation Most of our work starts from issues raised by polyomavirus, a small DNA tumor virus. Polyomaviruses subvert host cell mechanisms for its replication and transcription. The ability of the virus to transform is based on its early proteins: large T (LT), middle T (MT) and small T (ST) antigens and their actions in the cell.
See more information about the Schaffhausen Lab.
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