Bacillus subtilis & Clostridium difficile

Joseph Sorg
Postdoctoral Associate
Ph.D. University of Chicago, Department of Microbiology
B.S. Purdue University

Thesis Topic
Type III secretion blockades in Yersinia species.

Current Research
Sporulation and germination in Clostridium difficile

Publications

1. Riordan, KE., Sorg, JA., Berube, BJ., Schneewind, O. (2008). Impassable YscP substrates and their impact on the Yersinia enterocolitica type III pathway. J. Bacteriol. In press.
2. Sorg JA, Sonenshein AL. Bile salts and glycine as cogerminants for Clostridium difficile spores. J Bacteriol. 2008 Apr;190(7):2505-12. Epub 2008 Feb 1.
3. Sorg JA, Blaylock B, Schneewind O. Secretion signal recognition by YscN, the Yersinia type III secretion ATPase. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16490-5. Epub 2006 Oct 18.
4. Sorg JA, Miller NC, Marketon MM, Schneewind O. Rejection of impassable substrates by Yersinia type III secretion machines. J Bacteriol. 2005 Oct;187(20):7090-102.
5. Sorg JA, Miller NC, Schneewind O. Substrate recognition of type III secretion machines--testing the RNA signal hypothesis. Cell Microbiol. 2005 Sep;7(9):1217-25. Review.
6. Goss JW, Sorg JA, Ramamurthi KS, Ton-That H, Schneewind O. The secretion signal of YopN, a regulatory protein of the Yersinia enterocolitica type III secretion pathway. J Bacteriol. 2004 Sep;186(18):6320-4.
7. Cambronne ED, Sorg JA, Schneewind O. Binding of SycH chaperone to YscM1 and YscM2 activates effector yop expression in Yersinia enterocolitica. J Bacteriol. 2004 Feb;186(3):829-41.