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Behavior Core Services

 

Core services are provided in the Department of Laboratory Animal Medicine (DLAM) on the third floor of the South Cove building.

Layout of CNR Behavior Core, DLAM, S. Cove 3


 

 


The following behavioral assays are currently available:

Behavioral Functions, Neuropsychiatric Disorders Set-ups and equipment offered
Learning, Memory and Cognition Emotional memory
• Fear conditioning (contextual or cue-associated modalities)
Spatial memory
• Barnes maze
• Morris water maze
• Radial arm maze
• Spontaneous alteration (T maze) - "working memory"
• Novel object recognition
Motor activity
(baseline levels, or drug-abused effects)
Locomotor activity
• Home cage (photobeam breaks)
• Open-field arena (photobeam breaks)

Motor coordination and balance
• Rotarod test
Pain Reactivity to painful stimulation
• Tailflick test (spinal reflex)
• Hot plate test (supraspinal pain reflex)
Anxiety Anxiety-like behavior
• Elevated plus maze (automated)
• Open-field activity (photobeam breaks)
• Light/dark box (automated)
• Startle response (acoustic stimulus)
Depression / Mood Disorders Depressive-like behavior
• Porsolt forced swim test
• Tail suspension test
• Sucrose/saccharin preference
Schizophrenia Prepulse inhibition
• Acoustic startle response
Social Behavior Interactive behavior
• Social interaction test
• Three-chamber test
Drug Addiction Conditioned reward
• Conditioned place preference

Alcohol self-administration
• Preference (bottle-choice)
• Drinking in the dark

Locomotor activity
• Psychostimulant effects vs. depressant effects
• Tolerance and sensitization of psychomotor activity
Chronobiology Circadian rhythm
• Phase controlled wheel running
Metabolism Indirect calorimetry
• Energy expenditure (respirometry)
• Food intake
• Locomotor activity

Fees for Behavior Core Services

Please contact Jennifer Newman for additional information.

Imaging
Genomics
Electrophysiology
Behavior

Co-Directors
Jamie Maguire, PhD
Klaus Miczek, PhD

Core Manager
Jennifer Newman, PhD
(617.636.2490)

Scientific Advisor
Jane R. Taylor, PhD
(Yale University)

Location
South Cove 3

 
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Last updated: 05/02/2013